BRD-K79131428_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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46 genes differentially expressed following the BRD-K79131428_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABAT 4-aminobutyrate aminotransferase
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BEX1 brain expressed, X-linked 1
CLIC4 chloride intracellular channel 4
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
GDF15 growth differentiation factor 15
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
HBD hemoglobin, delta
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HSPA1A heat shock 70kDa protein 1A
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HYOU1 hypoxia up-regulated 1
IFI30 interferon, gamma-inducible protein 30
LYZ lysozyme
MAP7 microtubule-associated protein 7
MEST mesoderm specific transcript
PDIA4 protein disulfide isomerase family A, member 4
PRF1 perforin 1 (pore forming protein)
S100A8 S100 calcium binding protein A8
STEAP1 six transmembrane epithelial antigen of the prostate 1
TSC22D1 TSC22 domain family, member 1
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ASPN asporin
BST2 bone marrow stromal cell antigen 2
CCND1 cyclin D1
COL6A1 collagen, type VI, alpha 1
CXCL14 chemokine (C-X-C motif) ligand 14
GOLGA8A golgin A8 family, member A
GPM6B glycoprotein M6B
IFI27 interferon, alpha-inducible protein 27
IFI44L interferon-induced protein 44-like
IKZF1 IKAROS family zinc finger 1 (Ikaros)
LHFP lipoma HMGIC fusion partner
LRRC17 leucine rich repeat containing 17
MX1 MX dynamin-like GTPase 1
NR2F2 nuclear receptor subfamily 2, group F, member 2
PBX3 pre-B-cell leukemia homeobox 3
PODXL podocalyxin-like
PROSC proline synthetase co-transcribed homolog (bacterial)
S100A2 S100 calcium binding protein A2
SET SET nuclear proto-oncogene