BRD-K79239947_PF 573228_A375_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

90 genes differentially expressed following the BRD-K79239947_PF 573228_A375_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ANXA9 annexin A9
ATF3 activating transcription factor 3
BZW2 basic leucine zipper and W2 domains 2
CDC42 cell division cycle 42
CFB complement factor B
CSRP1 cysteine and glycine-rich protein 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
G3BP1 GTPase activating protein (SH3 domain) binding protein 1
GBP1 guanylate binding protein 1, interferon-inducible
H2BFS H2B histone family, member S (pseudogene)
HNMT histamine N-methyltransferase
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IL13RA1 interleukin 13 receptor, alpha 1
KIAA1598
LAPTM4B lysosomal protein transmembrane 4 beta
MEIS1 Meis homeobox 1
MYOF myoferlin
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIR pirin (iron-binding nuclear protein)
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
PSPH phosphoserine phosphatase
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
SIRT3 sirtuin 3
SLC22A18 solute carrier family 22, member 18
SNX2 sorting nexin 2
SOCS2 suppressor of cytokine signaling 2
SPON1 spondin 1, extracellular matrix protein
SSPN sarcospan
SUB1 SUB1 homolog (S. cerevisiae)
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
ZFPM2 zinc finger protein, FOG family member 2

decreased expression

Symbol Name
ACKR3 atypical chemokine receptor 3
ADGRL2 adhesion G protein-coupled receptor L2
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AQP3 aquaporin 3 (Gill blood group)
AUTS2 autism susceptibility candidate 2
AXL AXL receptor tyrosine kinase
BCL2A1 BCL2-related protein A1
BPIFA1 BPI fold containing family A, member 1
CA12 carbonic anhydrase XII
CD24 CD24 molecule
CD59 CD59 molecule, complement regulatory protein
CD9 CD9 molecule
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLPTM1 cleft lip and palate associated transmembrane protein 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
CSRP2 cysteine and glycine-rich protein 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
EZR ezrin
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FKBP11 FK506 binding protein 11, 19 kDa
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
HCAR3 hydroxycarboxylic acid receptor 3
HEATR1 HEAT repeat containing 1
IGFBP4 insulin-like growth factor binding protein 4
IGFBP7 insulin-like growth factor binding protein 7
IL1RN interleukin 1 receptor antagonist
IRS2 insulin receptor substrate 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRT14 keratin 14, type I
LTF lactotransferrin
LYPD3 LY6/PLAUR domain containing 3
MARCO macrophage receptor with collagenous structure
NAMPT nicotinamide phosphoribosyltransferase
NFIB nuclear factor I/B
PHKA1 phosphorylase kinase, alpha 1 (muscle)
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGS2 regulator of G-protein signaling 2
S100A12 S100 calcium binding protein A12
S100A2 S100 calcium binding protein A2
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SLC39A8 solute carrier family 39 (zinc transporter), member 8
SOD2 superoxide dismutase 2, mitochondrial
SPRR1A small proline-rich protein 1A
SPRR3 small proline-rich protein 3
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TEX10 testis expressed 10
TFF3 trefoil factor 3 (intestinal)
THBS4 thrombospondin 4
Funding