BRD-K79254416_decitabine_A549_24_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

17 genes differentially expressed following the BRD-K79254416_decitabine_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ATF5 activating transcription factor 5
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CTTN cortactin
MREG melanoregulin
THBS1 thrombospondin 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5AP arachidonate 5-lipoxygenase-activating protein
DAPK1 death-associated protein kinase 1
FAM134B family with sequence similarity 134, member B
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2
PTCH1 patched 1
SOD2 superoxide dismutase 2, mitochondrial
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
Funding