BRD-K79259477_KIN001-265_A375_24_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

69 genes differentially expressed following the BRD-K79259477_KIN001-265_A375_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADD3 adducin 3 (gamma)
C14ORF132 chromosome 14 open reading frame 132
CCNG2 cyclin G2
CFI complement factor I
FTH1 ferritin, heavy polypeptide 1
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GPX4 glutathione peroxidase 4
KIZ kizuna centrosomal protein
MFAP3L microfibrillar-associated protein 3-like
MFSD10 major facilitator superfamily domain containing 10
MSX1 msh homeobox 1
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NRCAM neuronal cell adhesion molecule
NUPR1 nuclear protein, transcriptional regulator, 1
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RGCC regulator of cell cycle
SCGB2A1 secretoglobin, family 2A, member 1
SQSTM1 sequestosome 1
ST13 suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
TRIM2 tripartite motif containing 2

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
AQP3 aquaporin 3 (Gill blood group)
CCND1 cyclin D1
CSTA cystatin A (stefin A)
CTGF connective tissue growth factor
CXCL14 chemokine (C-X-C motif) ligand 14
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DAXX death-domain associated protein
DEFB1 defensin, beta 1
DUSP6 dual specificity phosphatase 6
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FASTKD5 FAST kinase domains 5
FOSL1 FOS-like antigen 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLS glutaminase
HEATR1 HEAT repeat containing 1
HIST1H2BG histone cluster 1, H2bg
IER3 immediate early response 3
IGKC immunoglobulin kappa constant
IGL immunoglobulin lambda locus
IL7R interleukin 7 receptor
JCHAIN joining chain of multimeric IgA and IgM
KRT6B keratin 6B, type II
LYZ lysozyme
MARCKS myristoylated alanine-rich protein kinase C substrate
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MOK MOK protein kinase
MRPS2 mitochondrial ribosomal protein S2
MSH6 mutS homolog 6
NEFL neurofilament, light polypeptide
PAEP progestagen-associated endometrial protein
PHLDA2 pleckstrin homology-like domain, family A, member 2
POU2AF1 POU class 2 associating factor 1
RGS2 regulator of G-protein signaling 2
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A8 S100 calcium binding protein A8
S100A9 S100 calcium binding protein A9
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SOX11 SRY (sex determining region Y)-box 11
STX1A syntaxin 1A (brain)
TFPI2 tissue factor pathway inhibitor 2
TM4SF1 transmembrane 4 L six family member 1
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSPYL5 TSPY-like 5
Funding