| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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143 genes differentially expressed following the BRD-K79259477_KIN001-265_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABAT | 4-aminobutyrate aminotransferase |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALOX5 | arachidonate 5-lipoxygenase |
| AMACR | alpha-methylacyl-CoA racemase |
| ANPEP | alanyl (membrane) aminopeptidase |
| ASS1 | argininosuccinate synthase 1 |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BEX1 | brain expressed, X-linked 1 |
| CBS | cystathionine-beta-synthase |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
| CFB | complement factor B |
| CFI | complement factor I |
| CSTA | cystatin A (stefin A) |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DDB2 | damage-specific DNA binding protein 2, 48kDa |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DEFB1 | defensin, beta 1 |
| FADS1 | fatty acid desaturase 1 |
| FAM134B | family with sequence similarity 134, member B |
| FAM63A | family with sequence similarity 63, member A |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR3 | fibroblast growth factor receptor 3 |
| GPER1 | G protein-coupled estrogen receptor 1 |
| GSTA1 | glutathione S-transferase alpha 1 |
| GSTA4 | glutathione S-transferase alpha 4 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 |
| HCP5 | HLA complex P5 (non-protein coding) |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HMOX1 | heme oxygenase 1 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| ISYNA1 | inositol-3-phosphate synthase 1 |
| KCNJ15 | potassium channel, inwardly rectifying subfamily J, member 15 |
| LAMA3 | laminin, alpha 3 |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| METTL7A | methyltransferase like 7A |
| MMP10 | matrix metallopeptidase 10 |
| MMP7 | matrix metallopeptidase 7 |
| MSMO1 | methylsterol monooxygenase 1 |
| NRIP1 | nuclear receptor interacting protein 1 |
| PBLD | phenazine biosynthesis-like protein domain containing |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PYCARD | PYD and CARD domain containing |
| S100A8 | S100 calcium binding protein A8 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 |
| TMEM97 | transmembrane protein 97 |
| TSPYL5 | TSPY-like 5 |
| TST | thiosulfate sulfurtransferase (rhodanese) |
| Symbol | Name |
|---|---|
| ADAM9 | ADAM metallopeptidase domain 9 |
| AKAP12 | A kinase (PRKA) anchor protein 12 |
| ANXA1 | annexin A1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APP | amyloid beta (A4) precursor protein |
| AREG | amphiregulin |
| ASPH | aspartate beta-hydroxylase |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CD9 | CD9 molecule |
| COL1A2 | collagen, type I, alpha 2 |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CST3 | cystatin C |
| CTGF | connective tissue growth factor |
| CTSC | cathepsin C |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DUSP5 | dual specificity phosphatase 5 |
| DUSP6 | dual specificity phosphatase 6 |
| EGR1 | early growth response 1 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) |
| EMP1 | epithelial membrane protein 1 |
| ENO1 | enolase 1, (alpha) |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM198B | family with sequence similarity 198, member B |
| FBN1 | fibrillin 1 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FOSL1 | FOS-like antigen 1 |
| FOXF1 | forkhead box F1 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| HOXB6 | homeobox B6 |
| HPCAL1 | hippocalcin-like 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IER3 | immediate early response 3 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| IGHM | immunoglobulin heavy constant mu |
| ISG15 | ISG15 ubiquitin-like modifier |
| KRT18 | keratin 18, type I |
| KRT8 | keratin 8, type II |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MCL1 | myeloid cell leukemia 1 |
| MINA | MYC induced nuclear antigen |
| MT1E | metallothionein 1E |
| MT1G | metallothionein 1G |
| MT1HL1 | metallothionein 1H-like 1 |
| MT1X | metallothionein 1X |
| MT2A | metallothionein 2A |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLCB4 | phospholipase C, beta 4 |
| PNO1 | partner of NOB1 homolog (S. cerevisiae) |
| PRKCH | protein kinase C, eta |
| RFTN1 | raftlin, lipid raft linker 1 |
| RGCC | regulator of cell cycle |
| RPIA | ribose 5-phosphate isomerase A |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 |
| THBS1 | thrombospondin 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TJP2 | tight junction protein 2 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TM9SF3 | transmembrane 9 superfamily member 3 |
| TMEM2 | transmembrane protein 2 |
| TPM2 | tropomyosin 2 (beta) |
| TSPAN5 | tetraspanin 5 |
| VWF | von Willebrand factor |
| WARS | tryptophanyl-tRNA synthetase |
| XIST | X inactive specific transcript (non-protein coding) |
