BRD-K79353516_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

45 genes differentially expressed following the BRD-K79353516_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ATF3 activating transcription factor 3
BTG2 BTG family, member 2
C14ORF132 chromosome 14 open reading frame 132
CCL2 chemokine (C-C motif) ligand 2
CCND2 cyclin D2
CCNG1 cyclin G1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
DDB2 damage-specific DNA binding protein 2, 48kDa
DHRS2 dehydrogenase/reductase (SDR family) member 2
FAS Fas cell surface death receptor
FDXR ferredoxin reductase
FHL2 four and a half LIM domains 2
GDF15 growth differentiation factor 15
GSTM3 glutathione S-transferase mu 3 (brain)
HMOX1 heme oxygenase 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
PDGFA platelet-derived growth factor alpha polypeptide
RBP1 retinol binding protein 1, cellular
RPS27L ribosomal protein S27-like
SESN1 sestrin 1
SQSTM1 sequestosome 1
STC2 stanniocalcin 2
TRIM22 tripartite motif containing 22
TXNRD1 thioredoxin reductase 1
ZMAT3 zinc finger, matrin-type 3

decreased expression

Symbol Name
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
CCNB2 cyclin B2
CHGB chromogranin B
DEPTOR DEP domain containing MTOR-interacting protein
FKBP11 FK506 binding protein 11, 19 kDa
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IDO1 indoleamine 2,3-dioxygenase 1
IFITM1 interferon induced transmembrane protein 1
NEK2 NIMA-related kinase 2
S100A7 S100 calcium binding protein A7
SPARCL1 SPARC-like 1 (hevin)
TBC1D31 TBC1 domain family, member 31
TNS3 tensin 3
TRD T cell receptor delta locus
TRDV3 T cell receptor delta variable 3
UPK1B uroplakin 1B