BRD-K79459005_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

47 genes differentially expressed following the BRD-K79459005_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCA2 ATP-binding cassette, sub-family A (ABC1), member 2
APOD apolipoprotein D
FOLR1 folate receptor 1 (adult)
GUSBP3 glucuronidase, beta pseudogene 3
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)
HOPX HOP homeobox
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LAPTM4B lysosomal protein transmembrane 4 beta
LGALS8 lectin, galactoside-binding, soluble, 8
LOC100272216 uncharacterized LOC100272216
MAP7 microtubule-associated protein 7
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SCGB1D2 secretoglobin, family 1D, member 2
SCGB2A2 secretoglobin, family 2A, member 2
SMA4 glucuronidase, beta pseudogene
TUBB2A tubulin, beta 2A class IIa
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ALB albumin
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
EIF3A eukaryotic translation initiation factor 3, subunit A
FZD6 frizzled class receptor 6
GPRC5A G protein-coupled receptor, class C, group 5, member A
HIST1H2BD histone cluster 1, H2bd
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGF1R insulin-like growth factor 1 receptor
ITM2C integral membrane protein 2C
MBNL1 muscleblind-like splicing regulator 1
MDK midkine (neurite growth-promoting factor 2)
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
NAV2 neuron navigator 2
PLIN2 perilipin 2
PODXL podocalyxin-like
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta
REG1A regenerating islet-derived 1 alpha
RGS5 regulator of G-protein signaling 5
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SET SET nuclear proto-oncogene
SFRP1 secreted frizzled-related protein 1
TFPI2 tissue factor pathway inhibitor 2
ZBTB18 zinc finger and BTB domain containing 18
ZNF185 zinc finger protein 185 (LIM domain)