BRD-K79554012_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

47 genes differentially expressed following the BRD-K79554012_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
CHIC2 cysteine-rich hydrophobic domain 2
CRYZ crystallin, zeta (quinone reductase)
CXCL14 chemokine (C-X-C motif) ligand 14
DCN decorin
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase)
F2RL1 coagulation factor II (thrombin) receptor-like 1
FABP4 fatty acid binding protein 4, adipocyte
FHL1 four and a half LIM domains 1
G0S2 G0/G1 switch 2
GLRX glutaredoxin (thioltransferase)
HBB hemoglobin, beta
HSPA2 heat shock 70kDa protein 2
HSPB8 heat shock 22kDa protein 8
IGFBP7 insulin-like growth factor binding protein 7
ITM2A integral membrane protein 2A
LYZ lysozyme
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
MXRA7 matrix-remodelling associated 7
OAT ornithine aminotransferase
PLS3 plastin 3
PRSS3 protease, serine, 3
RGS5 regulator of G-protein signaling 5
S100A8 S100 calcium binding protein A8
S100P S100 calcium binding protein P
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SFRP1 secreted frizzled-related protein 1
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TSPAN13 tetraspanin 13
TSPAN8 tetraspanin 8
TUBA1A tubulin, alpha 1a
VCAM1 vascular cell adhesion molecule 1
VNN1 vanin 1

decreased expression

Symbol Name
ACSL3 acyl-CoA synthetase long-chain family member 3
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
HNMT histamine N-methyltransferase
LDLR low density lipoprotein receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRSS21 protease, serine, 21 (testisin)
SDC1 syndecan 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SNX7 sorting nexin 7
SPEN spen family transcriptional repressor
TRIB3 tribbles pseudokinase 3