BRD-K80094086_-666_HA1E_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

66 genes differentially expressed following the BRD-K80094086_-666_HA1E_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide
AIM1 absent in melanoma 1
AOX1 aldehyde oxidase 1
AQP9 aquaporin 9
ASCL1 achaete-scute family bHLH transcription factor 1
C6ORF62 chromosome 6 open reading frame 62
CCND2 cyclin D2
CD24 CD24 molecule
CLDN3 claudin 3
CRABP1 cellular retinoic acid binding protein 1
CRABP2 cellular retinoic acid binding protein 2
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DSE dermatan sulfate epimerase
DSP desmoplakin
ELOVL2 ELOVL fatty acid elongase 2
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FGFR1 fibroblast growth factor receptor 1
G0S2 G0/G1 switch 2
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HRASLS HRAS-like suppressor
MMP9 matrix metallopeptidase 9
MT1E metallothionein 1E
MT1F metallothionein 1F
MT1G metallothionein 1G
MT1H metallothionein 1H
MT1HL1 metallothionein 1H-like 1
MT1X metallothionein 1X
MT2A metallothionein 2A
NFIB nuclear factor I/B
RBP1 retinol binding protein 1, cellular
REG1A regenerating islet-derived 1 alpha
RORA RAR-related orphan receptor A
SEPT6 septin 6
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC35E3 solute carrier family 35, member E3
SPAG4 sperm associated antigen 4
STK10 serine/threonine kinase 10
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
ZNF586 zinc finger protein 586

decreased expression

Symbol Name
ATF3 activating transcription factor 3
CCNA1 cyclin A1
CCNF cyclin F
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CLIC4 chloride intracellular channel 4
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
ERBB2 erb-b2 receptor tyrosine kinase 2
FGFR2 fibroblast growth factor receptor 2
GADD45B growth arrest and DNA-damage-inducible, beta
GPRC5A G protein-coupled receptor, class C, group 5, member A
HOXA10 homeobox A10
HOXA5 homeobox A5
HOXC6 homeobox C6
JMJD6 jumonji domain containing 6
KRT13 keratin 13, type I
LIMCH1 LIM and calponin homology domains 1
MAP7 microtubule-associated protein 7
NPAS2 neuronal PAS domain protein 2
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RBM34 RNA binding motif protein 34
RGS5 regulator of G-protein signaling 5
S100A9 S100 calcium binding protein A9
SLPI secretory leukocyte peptidase inhibitor
TCF4 transcription factor 4
TRIM29 tripartite motif containing 29
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