BRD-K80431395_-666_SKB_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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63 genes differentially expressed following the BRD-K80431395_-666_SKB_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1
ABHD4 abhydrolase domain containing 4
ACSL3 acyl-CoA synthetase long-chain family member 3
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CBR3 carbonyl reductase 3
CLNS1A chloride channel, nucleotide-sensitive, 1A
COL4A5 collagen, type IV, alpha 5
DUSP4 dual specificity phosphatase 4
GRAMD3 GRAM domain containing 3
HLA-DMA major histocompatibility complex, class II, DM alpha
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11
HSPA1A heat shock 70kDa protein 1A
ICAM1 intercellular adhesion molecule 1
IFITM1 interferon induced transmembrane protein 1
KRT16 keratin 16, type I
KRT17 keratin 17, type I
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
NFE2 nuclear factor, erythroid 2
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
PALLD palladin, cytoskeletal associated protein
PI3 peptidase inhibitor 3, skin-derived
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma
PLAT plasminogen activator, tissue
PLEKHA5 pleckstrin homology domain containing, family A member 5
REXO2 RNA exonuclease 2
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
SRGN serglycin
TACSTD2 tumor-associated calcium signal transducer 2
TJP2 tight junction protein 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
ZFP36L2 ZFP36 ring finger protein-like 2

decreased expression

Symbol Name
ADGRG2 adhesion G protein-coupled receptor G2
AP1S2 adaptor-related protein complex 1, sigma 2 subunit
ASNS asparagine synthetase (glutamine-hydrolyzing)
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD24 CD24 molecule
CD38 CD38 molecule
CDC20 cell division cycle 20
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHMP4A charged multivesicular body protein 4A
COL11A1 collagen, type XI, alpha 1
COL1A2 collagen, type I, alpha 2
CPA3 carboxypeptidase A3 (mast cell)
CRIP1 cysteine-rich protein 1 (intestinal)
CRIP2 cysteine-rich protein 2
CSTA cystatin A (stefin A)
FKBP14 FK506 binding protein 14, 22 kDa
GNG11 guanine nucleotide binding protein (G protein), gamma 11
HOXB6 homeobox B6
HOXB7 homeobox B7
IGFBP5 insulin-like growth factor binding protein 5
MEF2C myocyte enhancer factor 2C
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
PHGDH phosphoglycerate dehydrogenase
PSAT1 phosphoserine aminotransferase 1
RPL37A ribosomal protein L37a
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae)
TDO2 tryptophan 2,3-dioxygenase
TMSB15A thymosin beta 15a
TYMS thymidylate synthetase
USP22 ubiquitin specific peptidase 22
VWF von Willebrand factor
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon