BRD-K80700417_SGI-1776_A549_24_h_10_um Gene Set
Genes
39 genes differentially expressed following the BRD-K80700417_SGI-1776_A549_24_h_10_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
ADAMDEC1
|
ADAM-like, decysin 1
|
ALDOC
|
aldolase C, fructose-bisphosphate
|
COLEC12
|
collectin sub-family member 12
|
DHCR24
|
24-dehydrocholesterol reductase
|
DHDDS
|
dehydrodolichyl diphosphate synthase
|
DUSP4
|
dual specificity phosphatase 4
|
ELOVL6
|
ELOVL fatty acid elongase 6
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
FDPS
|
farnesyl diphosphate synthase
|
GLUL
|
glutamate-ammonia ligase
|
GPNMB
|
glycoprotein (transmembrane) nmb
|
GPR137B
|
G protein-coupled receptor 137B
|
HMGCR
|
3-hydroxy-3-methylglutaryl-CoA reductase
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
IDI1
|
isopentenyl-diphosphate delta isomerase 1
|
INSIG1
|
insulin induced gene 1
|
LSS
|
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
|
MSMO1
|
methylsterol monooxygenase 1
|
NUPR1
|
nuclear protein, transcriptional regulator, 1
|
PHYH
|
phytanoyl-CoA 2-hydroxylase
|
RAP1GAP
|
RAP1 GTPase activating protein
|
SCD
|
stearoyl-CoA desaturase (delta-9-desaturase)
|
SETBP1
|
SET binding protein 1
|
SLC1A3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 3
|
SQLE
|
squalene epoxidase
|
TLR4
|
toll-like receptor 4
|
TRIB2
|
tribbles pseudokinase 2
|
TXNIP
|
thioredoxin interacting protein
|
decreased expression
Symbol |
Name |
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
CYR61
|
cysteine-rich, angiogenic inducer, 61
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
KRT15
|
keratin 15, type I
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
MYCBP
|
MYC binding protein
|
PEG10
|
paternally expressed 10
|
POLE3
|
polymerase (DNA directed), epsilon 3, accessory subunit
|
RGS4
|
regulator of G-protein signaling 4
|
S100A7
|
S100 calcium binding protein A7
|