BRD-K81473043_-666_A375_6.0_h_0.35_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

26 genes differentially expressed following the BRD-K81473043_-666_A375_6.0_h_0.35_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
BAG3 BCL2-associated athanogene 3
CLDN3 claudin 3
COL5A2 collagen, type V, alpha 2
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
HMOX1 heme oxygenase 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
TMEM97 transmembrane protein 97

decreased expression

Symbol Name
COL9A3 collagen, type IX, alpha 3
ERBB3 erb-b2 receptor tyrosine kinase 3
HOXA5 homeobox A5
IER3 immediate early response 3
KRT18 keratin 18, type I
MIA melanoma inhibitory activity
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB38 RAB38, member RAS oncogene family
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
S100A2 S100 calcium binding protein A2
S100B S100 calcium binding protein B
STK17A serine/threonine kinase 17a
TNC tenascin C
VGLL4 vestigial-like family member 4