Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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139 genes differentially expressed following the BRD-K81528515_nilotinib_A549_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADGRG2 | adhesion G protein-coupled receptor G2 |
AGR2 | anterior gradient 2 |
AHNAK | AHNAK nucleoprotein |
ALCAM | activated leukocyte cell adhesion molecule |
ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
ANKRD36B | ankyrin repeat domain 36B |
ANXA4 | annexin A4 |
C1S | complement component 1, s subcomponent |
C2CD5 | C2 calcium-dependent domain containing 5 |
C3 | complement component 3 |
CAV1 | caveolin 1, caveolae protein, 22kDa |
CD44 | CD44 molecule (Indian blood group) |
CD93 | CD93 molecule |
CHRDL1 | chordin-like 1 |
COL4A2 | collagen, type IV, alpha 2 |
DUSP4 | dual specificity phosphatase 4 |
EGFR | epidermal growth factor receptor |
EPHB2 | EPH receptor B2 |
ERGIC3 | ERGIC and golgi 3 |
F2R | coagulation factor II (thrombin) receptor |
FCGBP | Fc fragment of IgG binding protein |
FLRT2 | fibronectin leucine rich transmembrane protein 2 |
GALC | galactosylceramidase |
GALNT11 | polypeptide N-acetylgalactosaminyltransferase 11 |
GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
GPRC5B | G protein-coupled receptor, class C, group 5, member B |
GPX1 | glutathione peroxidase 1 |
GUSB | glucuronidase, beta |
HEBP1 | heme binding protein 1 |
IGFBP7 | insulin-like growth factor binding protein 7 |
IRS2 | insulin receptor substrate 2 |
ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) |
LTA4H | leukotriene A4 hydrolase |
MARCKSL1 | MARCKS-like 1 |
MDK | midkine (neurite growth-promoting factor 2) |
MSLN | mesothelin |
MTMR11 | myotubularin related protein 11 |
MXRA7 | matrix-remodelling associated 7 |
MYOF | myoferlin |
MYRF | myelin regulatory factor |
MZT2A | mitotic spindle organizing protein 2A |
NFIB | nuclear factor I/B |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
NMU | neuromedin U |
NPEPL1 | aminopeptidase-like 1 |
PECAM1 | platelet/endothelial cell adhesion molecule 1 |
PLAT | plasminogen activator, tissue |
PLSCR4 | phospholipid scramblase 4 |
PODXL | podocalyxin-like |
RBKS | ribokinase |
RBM47 | RNA binding motif protein 47 |
RBP1 | retinol binding protein 1, cellular |
SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SOD2 | superoxide dismutase 2, mitochondrial |
SOX4 | SRY (sex determining region Y)-box 4 |
SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
SRPX | sushi-repeat containing protein, X-linked |
SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
TCEA2 | transcription elongation factor A (SII), 2 |
TFF1 | trefoil factor 1 |
TFPI2 | tissue factor pathway inhibitor 2 |
TIMP1 | TIMP metallopeptidase inhibitor 1 |
TM4SF1 | transmembrane 4 L six family member 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
TRAPPC6A | trafficking protein particle complex 6A |
TST | thiosulfate sulfurtransferase (rhodanese) |
UGDH | UDP-glucose 6-dehydrogenase |
VAT1 | vesicle amine transport 1 |
VCAN | versican |
VEGFC | vascular endothelial growth factor C |
VWF | von Willebrand factor |
WT1 | Wilms tumor 1 |
ZFPM2 | zinc finger protein, FOG family member 2 |
Symbol | Name |
---|---|
ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 |
ACP5 | acid phosphatase 5, tartrate resistant |
AQP3 | aquaporin 3 (Gill blood group) |
ARG2 | arginase 2 |
ASNS | asparagine synthetase (glutamine-hydrolyzing) |
ATAD2 | ATPase family, AAA domain containing 2 |
AURKA | aurora kinase A |
CALML3 | calmodulin-like 3 |
CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) |
CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain |
CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma |
CHORDC1 | cysteine and histidine-rich domain (CHORD) containing 1 |
COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
CSTA | cystatin A (stefin A) |
CTH | cystathionine gamma-lyase |
CTSZ | cathepsin Z |
DDIT3 | DNA-damage-inducible transcript 3 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
FBP1 | fructose-1,6-bisphosphatase 1 |
FKBP14 | FK506 binding protein 14, 22 kDa |
GARS | glycyl-tRNA synthetase |
GCH1 | GTP cyclohydrolase 1 |
GOT1 | glutamic-oxaloacetic transaminase 1, soluble |
GPM6B | glycoprotein M6B |
HOXC10 | homeobox C10 |
IARS | isoleucyl-tRNA synthetase |
ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein |
IL1RN | interleukin 1 receptor antagonist |
IRX5 | iroquois homeobox 5 |
KRT13 | keratin 13, type I |
KRT5 | keratin 5, type II |
LEF1 | lymphoid enhancer-binding factor 1 |
LINC00341 | long intergenic non-protein coding RNA 341 |
LMO4 | LIM domain only 4 |
LTF | lactotransferrin |
MAL | mal, T-cell differentiation protein |
MAPK13 | mitogen-activated protein kinase 13 |
MARS | methionyl-tRNA synthetase |
MMP12 | matrix metallopeptidase 12 |
NGRN | neugrin, neurite outgrowth associated |
PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
PHGDH | phosphoglycerate dehydrogenase |
PSAT1 | phosphoserine aminotransferase 1 |
RCAN1 | regulator of calcineurin 1 |
S100A2 | S100 calcium binding protein A2 |
S100P | S100 calcium binding protein P |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SFN | stratifin |
SLC3A2 | solute carrier family 3 (amino acid transporter heavy chain), member 2 |
SPINK5 | serine peptidase inhibitor, Kazal type 5 |
SPRR1A | small proline-rich protein 1A |
STC2 | stanniocalcin 2 |
STK26 | serine/threonine protein kinase 26 |
TCL1A | T-cell leukemia/lymphoma 1A |
TFRC | transferrin receptor |
TNC | tenascin C |
TRIB3 | tribbles pseudokinase 3 |
TRIM2 | tripartite motif containing 2 |
VLDLR | very low density lipoprotein receptor |
WIF1 | WNT inhibitory factor 1 |