| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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174 genes differentially expressed following the BRD-K81814927_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADGRF5 | adhesion G protein-coupled receptor F5 |
| ADIRF | adipogenesis regulatory factor |
| AEBP1 | AE binding protein 1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANXA4 | annexin A4 |
| ANXA9 | annexin A9 |
| ATF3 | activating transcription factor 3 |
| BTG2 | BTG family, member 2 |
| CCND2 | cyclin D2 |
| CD52 | CD52 molecule |
| CECR1 | cat eye syndrome chromosome region, candidate 1 |
| CES1 | carboxylesterase 1 |
| CFD | complement factor D (adipsin) |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| COBLL1 | cordon-bleu WH2 repeat protein-like 1 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL4A5 | collagen, type IV, alpha 5 |
| CPE | carboxypeptidase E |
| CPM | carboxypeptidase M |
| CTSK | cathepsin K |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DCN | decorin |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| EFHD1 | EF-hand domain family, member D1 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGR1 | early growth response 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| EPAS1 | endothelial PAS domain protein 1 |
| ESRP1 | epithelial splicing regulatory protein 1 |
| EXPH5 | exophilin 5 |
| F11R | F11 receptor |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FGFR3 | fibroblast growth factor receptor 3 |
| FILIP1L | filamin A interacting protein 1-like |
| FRY | furry homolog (Drosophila) |
| GLT8D2 | glycosyltransferase 8 domain containing 2 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IRF6 | interferon regulatory factor 6 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 |
| KIAA1598 | |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LPAR6 | lysophosphatidic acid receptor 6 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAOB | monoamine oxidase B |
| MDFIC | MyoD family inhibitor domain containing |
| MEF2C | myocyte enhancer factor 2C |
| MPZL2 | myelin protein zero-like 2 |
| OLFM4 | olfactomedin 4 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
| PECAM1 | platelet/endothelial cell adhesion molecule 1 |
| PI4KA | phosphatidylinositol 4-kinase, catalytic, alpha |
| PON3 | paraoxonase 3 |
| PRKCI | protein kinase C, iota |
| PRSS16 | protease, serine, 16 (thymus) |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RCAN2 | regulator of calcineurin 2 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RGCC | regulator of cell cycle |
| RGS16 | regulator of G-protein signaling 16 |
| RGS5 | regulator of G-protein signaling 5 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C |
| SEPT2 | septin 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SOX17 | SRY (sex determining region Y)-box 17 |
| SPTSSA | serine palmitoyltransferase, small subunit A |
| STS | steroid sulfatase (microsomal), isozyme S |
| SULF1 | sulfatase 1 |
| THBS2 | thrombospondin 2 |
| THY1 | Thy-1 cell surface antigen |
| TMEM35 | transmembrane protein 35 |
| TMSB15A | thymosin beta 15a |
| UGP2 | UDP-glucose pyrophosphorylase 2 |
| VNN1 | vanin 1 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WFDC1 | WAP four-disulfide core domain 1 |
| WLS | wntless Wnt ligand secretion mediator |
| ZNF117 | zinc finger protein 117 |
| Symbol | Name |
|---|---|
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ARFIP2 | ADP-ribosylation factor interacting protein 2 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| AURKA | aurora kinase A |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC25A | cell division cycle 25A |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDCA4 | cell division cycle associated 4 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHPT1 | choline phosphotransferase 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CTTN | cortactin |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CYTL1 | cytokine-like 1 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DYNLL1 | dynein, light chain, LC8-type 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EXOSC4 | exosome component 4 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FOSL1 | FOS-like antigen 1 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HN1 | hematological and neurological expressed 1 |
| HOXC6 | homeobox C6 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IL1R2 | interleukin 1 receptor, type II |
| JADE1 | jade family PHD finger 1 |
| JMJD6 | jumonji domain containing 6 |
| KRT10 | keratin 10, type I |
| MARCKSL1 | MARCKS-like 1 |
| MCL1 | myeloid cell leukemia 1 |
| MIA | melanoma inhibitory activity |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NET1 | neuroepithelial cell transforming 1 |
| NUP62 | nucleoporin 62kDa |
| PFKP | phosphofructokinase, platelet |
| PPIF | peptidylprolyl isomerase F |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 |
| RBM14 | RNA binding motif protein 14 |
| RBM34 | RNA binding motif protein 34 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RPL27A | ribosomal protein L27a |
| RPL36 | ribosomal protein L36 |
| RPL36AL | ribosomal protein L36a-like |
| RPL37A | ribosomal protein L37a |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPS11 | ribosomal protein S11 |
| RPS26 | ribosomal protein S26 |
| RPS27L | ribosomal protein S27-like |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) |
| RUNX3 | runt-related transcription factor 3 |
| S100A2 | S100 calcium binding protein A2 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 |
| SLC35F2 | solute carrier family 35, member F2 |
| SLIRP | SRA stem-loop interacting RNA binding protein |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SQSTM1 | sequestosome 1 |
| SRGN | serglycin |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMM13 | translocase of inner mitochondrial membrane 13 homolog (yeast) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM2 | transmembrane protein 2 |
| TNPO1 | transportin 1 |
| TRAPPC3 | trafficking protein particle complex 3 |
| TXLNA | taxilin alpha |
| TXNDC9 | thioredoxin domain containing 9 |
| UBE2S | ubiquitin-conjugating enzyme E2S |
