Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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61 genes differentially expressed following the BRD-K82594686_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ALOX5 | arachidonate 5-lipoxygenase |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CA2 | carbonic anhydrase II |
CD200 | CD200 molecule |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
DPP4 | dipeptidyl-peptidase 4 |
ELANE | elastase, neutrophil expressed |
GNLY | granulysin |
GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
HBB | hemoglobin, beta |
HHEX | hematopoietically expressed homeobox |
KIAA1598 | |
KLRB1 | killer cell lectin-like receptor subfamily B, member 1 |
KRT18 | keratin 18, type I |
LITAF | lipopolysaccharide-induced TNF factor |
LOC100505650 | uncharacterized LOC100505650 |
MNDA | myeloid cell nuclear differentiation antigen |
MYRF | myelin regulatory factor |
NNMT | nicotinamide N-methyltransferase |
PMM2 | phosphomannomutase 2 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
QPCT | glutaminyl-peptide cyclotransferase |
RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 |
RTN1 | reticulon 1 |
SCGB1D2 | secretoglobin, family 1D, member 2 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
SRGN | serglycin |
TARP | TCR gamma alternate reading frame protein |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
TGFA | transforming growth factor, alpha |
TGM2 | transglutaminase 2 |
TMSB15A | thymosin beta 15a |
VAMP8 | vesicle-associated membrane protein 8 |
Symbol | Name |
---|---|
ADD3 | adducin 3 (gamma) |
BST2 | bone marrow stromal cell antigen 2 |
CD59 | CD59 molecule, complement regulatory protein |
EFNB2 | ephrin-B2 |
FABP7 | fatty acid binding protein 7, brain |
FOLR1 | folate receptor 1 (adult) |
GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) |
GPM6B | glycoprotein M6B |
HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
LYPLA1 | lysophospholipase I |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 |
PFN2 | profilin 2 |
PTN | pleiotrophin |
RPL27A | ribosomal protein L27a |
RPS11 | ribosomal protein S11 |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
THBS1 | thrombospondin 1 |
TSPAN8 | tetraspanin 8 |
TUBB2B | tubulin, beta 2B class IIb |
TWIST1 | twist family bHLH transcription factor 1 |
UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |