BRD-K82823804_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

89 genes differentially expressed following the BRD-K82823804_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACKR3 atypical chemokine receptor 3
ADIRF adipogenesis regulatory factor
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2
ATF4 activating transcription factor 4
C6ORF62 chromosome 6 open reading frame 62
CAPG capping protein (actin filament), gelsolin-like
CBS cystathionine-beta-synthase
CCNA1 cyclin A1
CCNG2 cyclin G2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CKB creatine kinase, brain
CLIC3 chloride intracellular channel 3
CPE carboxypeptidase E
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ENO1 enolase 1, (alpha)
ESRP1 epithelial splicing regulatory protein 1
EVI2A ecotropic viral integration site 2A
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
H1F0 H1 histone family, member 0
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IDO1 indoleamine 2,3-dioxygenase 1
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
JUN jun proto-oncogene
KIF1A kinesin family member 1A
LMO3 LIM domain only 3 (rhombotin-like 2)
MAOA monoamine oxidase A
MME membrane metallo-endopeptidase
NUPR1 nuclear protein, transcriptional regulator, 1
OARD1 O-acyl-ADP-ribose deacylase 1
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial)
PCP4 Purkinje cell protein 4
PEG3 paternally expressed 3
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A14 S100 calcium binding protein A14
SCP2 sterol carrier protein 2
SNX11 sorting nexin 11
TNNT1 troponin T type 1 (skeletal, slow)
TSC22D3 TSC22 domain family, member 3
VEGFA vascular endothelial growth factor A
ZNF586 zinc finger protein 586
ZSCAN18 zinc finger and SCAN domain containing 18

decreased expression

Symbol Name
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A3 aldehyde dehydrogenase 1 family, member A3
AMACR alpha-methylacyl-CoA racemase
APOD apolipoprotein D
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CCNF cyclin F
CDC25A cell division cycle 25A
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
COL4A2 collagen, type IV, alpha 2
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL5 chemokine (C-X-C motif) ligand 5
CXCL6 chemokine (C-X-C motif) ligand 6
CXCL8 chemokine (C-X-C motif) ligand 8
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM57A family with sequence similarity 57, member A
FSTL1 follistatin-like 1
FUT8 fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
FZD7 frizzled class receptor 7
HSPA1A heat shock 70kDa protein 1A
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IL13RA2 interleukin 13 receptor, alpha 2
LAMB1 laminin, beta 1
MMP7 matrix metallopeptidase 7
NFIB nuclear factor I/B
PI3 peptidase inhibitor 3, skin-derived
QPCT glutaminyl-peptide cyclotransferase
RPIA ribose 5-phosphate isomerase A
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
SPTBN1 spectrin, beta, non-erythrocytic 1
STOM stomatin
TBC1D4 TBC1 domain family, member 4
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TMEM2 transmembrane protein 2
WNT5A wingless-type MMTV integration site family, member 5A