Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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84 genes differentially expressed following the BRD-K82928847_rocilinostat_HEPG2_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AHNAK | AHNAK nucleoprotein |
ARL3 | ADP-ribosylation factor-like 3 |
ARL6IP5 | ADP-ribosylation factor-like 6 interacting protein 5 |
ARMCX2 | armadillo repeat containing, X-linked 2 |
CCND2 | cyclin D2 |
CDC42 | cell division cycle 42 |
CORO1C | coronin, actin binding protein, 1C |
DAD1 | defender against cell death 1 |
DNALI1 | dynein, axonemal, light intermediate chain 1 |
DUSP6 | dual specificity phosphatase 6 |
ESR1 | estrogen receptor 1 |
EXOSC4 | exosome component 4 |
FXYD6 | FXYD domain containing ion transport regulator 6 |
GLOD4 | glyoxalase domain containing 4 |
HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
IFI6 | interferon, alpha-inducible protein 6 |
IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
IRF9 | interferon regulatory factor 9 |
ISG15 | ISG15 ubiquitin-like modifier |
KRT7 | keratin 7, type II |
LOC100505650 | uncharacterized LOC100505650 |
LRP10 | low density lipoprotein receptor-related protein 10 |
MMP7 | matrix metallopeptidase 7 |
NFKBIB | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta |
PALLD | palladin, cytoskeletal associated protein |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PIH1D1 | PIH1 domain containing 1 |
PTN | pleiotrophin |
RBP1 | retinol binding protein 1, cellular |
RPL27A | ribosomal protein L27a |
RPS11 | ribosomal protein S11 |
S100A6 | S100 calcium binding protein A6 |
SCGB2A1 | secretoglobin, family 2A, member 1 |
SCGB2A2 | secretoglobin, family 2A, member 2 |
SERINC5 | serine incorporator 5 |
SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
SOX11 | SRY (sex determining region Y)-box 11 |
SPON1 | spondin 1, extracellular matrix protein |
TACSTD2 | tumor-associated calcium signal transducer 2 |
TFF1 | trefoil factor 1 |
TGM2 | transglutaminase 2 |
TNC | tenascin C |
TUBA1A | tubulin, alpha 1a |
WBP1L | WW domain binding protein 1-like |
WNT5A | wingless-type MMTV integration site family, member 5A |
XIST | X inactive specific transcript (non-protein coding) |
ZFP36L2 | ZFP36 ring finger protein-like 2 |
Symbol | Name |
---|---|
ADI1 | acireductone dioxygenase 1 |
AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
ATMIN | ATM interactor |
C1ORF115 | chromosome 1 open reading frame 115 |
C2CD5 | C2 calcium-dependent domain containing 5 |
CDKN2C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha |
CSTA | cystatin A (stefin A) |
CTBP1 | C-terminal binding protein 1 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
FAM129A | family with sequence similarity 129, member A |
GABRE | gamma-aminobutyric acid (GABA) A receptor, epsilon |
GPI | glucose-6-phosphate isomerase |
HBB | hemoglobin, beta |
HCAR3 | hydroxycarboxylic acid receptor 3 |
IGKV4-1 | immunoglobulin kappa variable 4-1 |
MEOX2 | mesenchyme homeobox 2 |
MTCL1 | microtubule crosslinking factor 1 |
NAMPT | nicotinamide phosphoribosyltransferase |
NREP | neuronal regeneration related protein |
PCSK6 | proprotein convertase subtilisin/kexin type 6 |
PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
PPIC | peptidylprolyl isomerase C (cyclophilin C) |
PROS1 | protein S (alpha) |
PTK2 | protein tyrosine kinase 2 |
RTN1 | reticulon 1 |
S100A12 | S100 calcium binding protein A12 |
S100A8 | S100 calcium binding protein A8 |
SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
VDAC1 | voltage-dependent anion channel 1 |
VWF | von Willebrand factor |