BRD-K82971429_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

60 genes differentially expressed following the BRD-K82971429_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AHR aryl hydrocarbon receptor
AREG amphiregulin
ATF3 activating transcription factor 3
BHLHE40 basic helix-loop-helix family, member e40
CD24 CD24 molecule
CSRP1 cysteine and glycine-rich protein 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1
DDIT4 DNA-damage-inducible transcript 4
DSP desmoplakin
DUSP4 dual specificity phosphatase 4
DUSP5 dual specificity phosphatase 5
DUSP6 dual specificity phosphatase 6
EREG epiregulin
FADS1 fatty acid desaturase 1
FN1 fibronectin 1
FOSL1 FOS-like antigen 1
FOSL2 FOS-like antigen 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER3 immediate early response 3
IGF1R insulin-like growth factor 1 receptor
INSIG1 insulin induced gene 1
KLF6 Kruppel-like factor 6
KLF9 Kruppel-like factor 9
KRT19 keratin 19, type I
LDLR low density lipoprotein receptor
LRRC17 leucine rich repeat containing 17
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MSMO1 methylsterol monooxygenase 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NAMPT nicotinamide phosphoribosyltransferase
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NPC1 Niemann-Pick disease, type C1
NR4A2 nuclear receptor subfamily 4, group A, member 2
PEG10 paternally expressed 10
PER1 period circadian clock 1
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PIP prolactin-induced protein
PLAU plasminogen activator, urokinase
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SDC4 syndecan 4
SFRP4 secreted frizzled-related protein 4
SIK1 salt-inducible kinase 1
SIRT3 sirtuin 3
SMAD3 SMAD family member 3
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
THBS2 thrombospondin 2
TIMP3 TIMP metallopeptidase inhibitor 3
TNFAIP6 tumor necrosis factor, alpha-induced protein 6

decreased expression

Symbol Name
FYB FYN binding protein
IGFBP5 insulin-like growth factor binding protein 5
IL13RA2 interleukin 13 receptor, alpha 2
LUC7L3 LUC7-like 3 (S. cerevisiae)
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
Funding