BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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52 genes differentially expressed following the BRD-K83354763_NF-kB Activation Inhibitor II, JSH-23_HA1E_24.0_h_6.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRE5 adhesion G protein-coupled receptor E5
AMDHD2 amidohydrolase domain containing 2
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COG7 component of oligomeric golgi complex 7
CRABP1 cellular retinoic acid binding protein 1
DPP4 dipeptidyl-peptidase 4
GAL galanin/GMAP prepropeptide
GMFG glia maturation factor, gamma
GRB7 growth factor receptor-bound protein 7
IFNAR1 interferon (alpha, beta and omega) receptor 1
IGLL1 immunoglobulin lambda-like polypeptide 1
LAPTM5 lysosomal protein transmembrane 5
NT5E 5'-nucleotidase, ecto (CD73)
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
PMM2 phosphomannomutase 2
PRKX protein kinase, X-linked
PRUNE2 prune homolog 2 (Drosophila)
RFTN1 raftlin, lipid raft linker 1
RGCC regulator of cell cycle

decreased expression

Symbol Name
ABHD4 abhydrolase domain containing 4
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
C8ORF4 chromosome 8 open reading frame 4
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCL2 chemokine (C-C motif) ligand 2
CD59 CD59 molecule, complement regulatory protein
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CH25H cholesterol 25-hydroxylase
CLIC3 chloride intracellular channel 3
CST3 cystatin C
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DKK1 dickkopf WNT signaling pathway inhibitor 1
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
FBLN1 fibulin 1
GREB1 growth regulation by estrogen in breast cancer 1
GSTA4 glutathione S-transferase alpha 4
GSTM3 glutathione S-transferase mu 3 (brain)
KLF10 Kruppel-like factor 10
KLF4 Kruppel-like factor 4 (gut)
MYO6 myosin VI
NCBP2 nuclear cap binding protein subunit 2, 20kDa
NPC2 Niemann-Pick disease, type C2
PDLIM1 PDZ and LIM domain 1
PLS3 plastin 3
RAB40B RAB40B, member RAS oncogene family
RPS4Y1 ribosomal protein S4, Y-linked 1
S100A10 S100 calcium binding protein A10
SIAH2 siah E3 ubiquitin protein ligase 2
SIK1 salt-inducible kinase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
TPD52L1 tumor protein D52-like 1