BRD-K83509924_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

52 genes differentially expressed following the BRD-K83509924_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ALOX5 arachidonate 5-lipoxygenase
CD40 CD40 molecule, TNF receptor superfamily member 5
CD93 CD93 molecule
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EIF5A eukaryotic translation initiation factor 5A
EXT1 exostosin glycosyltransferase 1
FAM69A family with sequence similarity 69, member A
FGFR2 fibroblast growth factor receptor 2
IGL immunoglobulin lambda locus
JCHAIN joining chain of multimeric IgA and IgM
LOC100505650 uncharacterized LOC100505650
MEST mesoderm specific transcript
MME membrane metallo-endopeptidase
MNDA myeloid cell nuclear differentiation antigen
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
PDZK1IP1 PDZK1 interacting protein 1
POU2AF1 POU class 2 associating factor 1
QPCT glutaminyl-peptide cyclotransferase
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RGCC regulator of cell cycle
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TRIB2 tribbles pseudokinase 2
VCAN versican

decreased expression

Symbol Name
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CD59 CD59 molecule, complement regulatory protein
DACH1 dachshund family transcription factor 1
EFNB2 ephrin-B2
EGFR epidermal growth factor receptor
FAM46A family with sequence similarity 46, member A
FOLR1 folate receptor 1 (adult)
GOLIM4 golgi integral membrane protein 4
IFI27 interferon, alpha-inducible protein 27
IL13RA2 interleukin 13 receptor, alpha 2
IL6R interleukin 6 receptor
KIAA0125 KIAA0125
LRRN3 leucine rich repeat neuronal 3
MAP7 microtubule-associated protein 7
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
NRIP1 nuclear receptor interacting protein 1
PLTP phospholipid transfer protein
PRDX4 peroxiredoxin 4
QDPR quinoid dihydropteridine reductase
RPS11 ribosomal protein S11
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SRPX sushi-repeat containing protein, X-linked
TIMP3 TIMP metallopeptidase inhibitor 3
TSPAN13 tetraspanin 13
ZFP36L2 ZFP36 ring finger protein-like 2