Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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97 genes differentially expressed following the BRD-K83509924_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ACAT2 | acetyl-CoA acetyltransferase 2 |
ACPP | acid phosphatase, prostate |
ARG2 | arginase 2 |
BID | BH3 interacting domain death agonist |
CCND2 | cyclin D2 |
CD40 | CD40 molecule, TNF receptor superfamily member 5 |
CEP57 | centrosomal protein 57kDa |
CHGB | chromogranin B |
COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
CSTA | cystatin A (stefin A) |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DES | desmin |
FGF13 | fibroblast growth factor 13 |
GABRP | gamma-aminobutyric acid (GABA) A receptor, pi |
H1F0 | H1 histone family, member 0 |
HBB | hemoglobin, beta |
HIST1H2BG | histone cluster 1, H2bg |
HOXC6 | homeobox C6 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA8 | heat shock 70kDa protein 8 |
IRS2 | insulin receptor substrate 2 |
ISG20 | interferon stimulated exonuclease gene 20kDa |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
MAN1A1 | mannosidase, alpha, class 1A, member 1 |
MAOA | monoamine oxidase A |
MAP7 | microtubule-associated protein 7 |
MPO | myeloperoxidase |
MT1F | metallothionein 1F |
MT1G | metallothionein 1G |
MT1M | metallothionein 1M |
NPY1R | neuropeptide Y receptor Y1 |
OLFM4 | olfactomedin 4 |
OSBPL10 | oxysterol binding protein-like 10 |
PF4 | platelet factor 4 |
PLIN2 | perilipin 2 |
PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform |
PTK2 | protein tyrosine kinase 2 |
QPCT | glutaminyl-peptide cyclotransferase |
RAMP1 | receptor (G protein-coupled) activity modifying protein 1 |
RPL39L | ribosomal protein L39-like |
RTN1 | reticulon 1 |
S100P | S100 calcium binding protein P |
SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
SORBS2 | sorbin and SH3 domain containing 2 |
STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
TGFBI | transforming growth factor, beta-induced, 68kDa |
TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
TSPYL5 | TSPY-like 5 |
WNT4 | wingless-type MMTV integration site family, member 4 |
XYLT1 | xylosyltransferase I |
Symbol | Name |
---|---|
ABLIM1 | actin binding LIM protein 1 |
AHNAK2 | AHNAK nucleoprotein 2 |
AK4 | adenylate kinase 4 |
BST2 | bone marrow stromal cell antigen 2 |
CA12 | carbonic anhydrase XII |
CFH | complement factor H |
CLU | clusterin |
CNPY3 | canopy FGF signaling regulator 3 |
CTSB | cathepsin B |
DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
DEFB1 | defensin, beta 1 |
DHRS2 | dehydrogenase/reductase (SDR family) member 2 |
EHBP1 | EH domain binding protein 1 |
EIF5 | eukaryotic translation initiation factor 5 |
ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
EREG | epiregulin |
FBN1 | fibrillin 1 |
GBP1 | guanylate binding protein 1, interferon-inducible |
IVNS1ABP | influenza virus NS1A binding protein |
KCTD12 | potassium channel tetramerization domain containing 12 |
LRRC15 | leucine rich repeat containing 15 |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MFAP2 | microfibrillar-associated protein 2 |
MXRA5 | matrix-remodelling associated 5 |
NREP | neuronal regeneration related protein |
PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
PDZD2 | PDZ domain containing 2 |
PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
PITX1 | paired-like homeodomain 1 |
PLS3 | plastin 3 |
POSTN | periostin, osteoblast specific factor |
PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 |
PTN | pleiotrophin |
RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
RALGDS | ral guanine nucleotide dissociation stimulator |
RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
S100A2 | S100 calcium binding protein A2 |
SEPP1 | selenoprotein P, plasma, 1 |
SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
SLPI | secretory leukocyte peptidase inhibitor |
SNX7 | sorting nexin 7 |
SYBU | syntabulin (syntaxin-interacting) |
TNS3 | tensin 3 |
TSPAN3 | tetraspanin 3 |
VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) |