BRD-K83972459_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

91 genes differentially expressed following the BRD-K83972459_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
A2M alpha-2-macroglobulin
ANO1 anoctamin 1, calcium activated chloride channel
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BTG1 B-cell translocation gene 1, anti-proliferative
BTG2 BTG family, member 2
CADM1 cell adhesion molecule 1
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CEMIP cell migration inducing protein, hyaluronan binding
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL11A1 collagen, type XI, alpha 1
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DAPK1 death-associated protein kinase 1
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
DHCR7 7-dehydrocholesterol reductase
DHDDS dehydrodolichyl diphosphate synthase
EGR2 early growth response 2
EGR3 early growth response 3
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1
ETV1 ets variant 1
GADD45B growth arrest and DNA-damage-inducible, beta
GAS1 growth arrest-specific 1
HDAC6 histone deacetylase 6
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMGB2 high mobility group box 2
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
IER5 immediate early response 5
INSIG1 insulin induced gene 1
KDM3A lysine (K)-specific demethylase 3A
KDM5D lysine (K)-specific demethylase 5D
KIAA0513 KIAA0513
LGMN legumain
LRRC15 leucine rich repeat containing 15
MAN2B1 mannosidase, alpha, class 2B, member 1
MARCKSL1 MARCKS-like 1
MDFIC MyoD family inhibitor domain containing
MGP matrix Gla protein
MMP1 matrix metallopeptidase 1
NID2 nidogen 2 (osteonidogen)
NPC1 Niemann-Pick disease, type C1
NR4A3 nuclear receptor subfamily 4, group A, member 3
OSR2 odd-skipped related transciption factor 2
PEG3 paternally expressed 3
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
PTPRO protein tyrosine phosphatase, receptor type, O
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RBP1 retinol binding protein 1, cellular
RGS10 regulator of G-protein signaling 10
RPS4Y1 ribosomal protein S4, Y-linked 1
SAT1 spermidine/spermine N1-acetyltransferase 1
SCGB2A2 secretoglobin, family 2A, member 2
SELL selectin L
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
THBS4 thrombospondin 4
TNNT1 troponin T type 1 (skeletal, slow)
TRPS1 trichorhinophalangeal syndrome I
UBR4 ubiquitin protein ligase E3 component n-recognin 4
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)
WIPI1 WD repeat domain, phosphoinositide interacting 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
AKR1C3 aldo-keto reductase family 1, member C3
ANP32A acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
EXT1 exostosin glycosyltransferase 1
FERMT1 fermitin family member 1
FLT3 fms-related tyrosine kinase 3
GSAP gamma-secretase activating protein
HACD3 3-hydroxyacyl-CoA dehydratase 3
HOXA10 homeobox A10
HSPA8 heat shock 70kDa protein 8
IGFBP3 insulin-like growth factor binding protein 3
IGFBP6 insulin-like growth factor binding protein 6
JADE2 jade family PHD finger 2
KRT18 keratin 18, type I
LAPTM4B lysosomal protein transmembrane 4 beta
MECOM MDS1 and EVI1 complex locus
MOK MOK protein kinase
NR2F6 nuclear receptor subfamily 2, group F, member 6
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PRSS23 protease, serine, 23
RAB13 RAB13, member RAS oncogene family
REXO2 RNA exonuclease 2
RGS5 regulator of G-protein signaling 5
TFPI2 tissue factor pathway inhibitor 2
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
VCAN versican
XAF1 XIAP associated factor 1
XIST X inactive specific transcript (non-protein coding)