BRD-K84709232_Caffeic acid phenethyl ester_PC3_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K84709232_Caffeic acid phenethyl ester_PC3_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AK4 adenylate kinase 4
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
C4BPA complement component 4 binding protein, alpha
CA12 carbonic anhydrase XII
CRYAB crystallin, alpha B
CXCL2 chemokine (C-X-C motif) ligand 2
DDIT4 DNA-damage-inducible transcript 4
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
EGLN3 egl-9 family hypoxia-inducible factor 3
EIF1 eukaryotic translation initiation factor 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FADS1 fatty acid desaturase 1
FAM57A family with sequence similarity 57, member A
FOLR1 folate receptor 1 (adult)
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GCLM glutamate-cysteine ligase, modifier subunit
GJA1 gap junction protein, alpha 1, 43kDa
GPRC5A G protein-coupled receptor, class C, group 5, member A
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPA8 heat shock 70kDa protein 8
IER5 immediate early response 5
JCHAIN joining chain of multimeric IgA and IgM
KRT17 keratin 17, type I
LOX lysyl oxidase
MFSD10 major facilitator superfamily domain containing 10
NDRG1 N-myc downstream regulated 1
NPC1 Niemann-Pick disease, type C1
NUCB2 nucleobindin 2
P3H2 prolyl 3-hydroxylase 2
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
PLIN2 perilipin 2
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
PROM1 prominin 1
PTHLH parathyroid hormone-like hormone
RNASET2 ribonuclease T2
RTN2 reticulon 2
S100P S100 calcium binding protein P
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFN stratifin
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SQSTM1 sequestosome 1
SRGN serglycin
TRAM1 translocation associated membrane protein 1
VEGFA vascular endothelial growth factor A
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
APLP2 amyloid beta (A4) precursor-like protein 2
CXCL9 chemokine (C-X-C motif) ligand 9
DPYSL3 dihydropyrimidinase-like 3
GUCY1A3 guanylate cyclase 1, soluble, alpha 3
IL1B interleukin 1, beta
MXRA5 matrix-remodelling associated 5
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
SVIL supervillin
TSPAN8 tetraspanin 8
VCAN versican
Funding