BRD-K84937637_A-275_A549_24.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
Similar Terms
Downloads & Tools

Genes

204 genes differentially expressed following the BRD-K84937637_A-275_A549_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDOB aldolase B, fructose-bisphosphate
ASPN asporin
ASS1 argininosuccinate synthase 1
ATF3 activating transcription factor 3
BHLHE41 basic helix-loop-helix family, member e41
BTG3 BTG family, member 3
CD52 CD52 molecule
CDC5L cell division cycle 5-like
CEP57 centrosomal protein 57kDa
CGRRF1 cell growth regulator with ring finger domain 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
CPA3 carboxypeptidase A3 (mast cell)
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CXADR coxsackie virus and adenovirus receptor
DAPK3 death-associated protein kinase 3
DDIT3 DNA-damage-inducible transcript 3
DHCR24 24-dehydrocholesterol reductase
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DPYSL3 dihydropyrimidinase-like 3
EGR1 early growth response 1
EVI2A ecotropic viral integration site 2A
F11R F11 receptor
F13A1 coagulation factor XIII, A1 polypeptide
FOS FBJ murine osteosarcoma viral oncogene homolog
GADD45B growth arrest and DNA-damage-inducible, beta
GAL galanin/GMAP prepropeptide
GEM GTP binding protein overexpressed in skeletal muscle
GREM1 gremlin 1, DAN family BMP antagonist
HOMER3 homer scaffolding protein 3
HOXC6 homeobox C6
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IGHD immunoglobulin heavy constant delta
IGHM immunoglobulin heavy constant mu
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
ISG15 ISG15 ubiquitin-like modifier
JUN jun proto-oncogene
KDM3A lysine (K)-specific demethylase 3A
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT20 keratin 20, type I
LGALS8 lectin, galactoside-binding, soluble, 8
LMO3 LIM domain only 3 (rhombotin-like 2)
LRMP lymphoid-restricted membrane protein
MAP1LC3B microtubule-associated protein 1 light chain 3 beta
MCTP1 multiple C2 domains, transmembrane 1
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MME membrane metallo-endopeptidase
MMP3 matrix metallopeptidase 3
MOSPD1 motile sperm domain containing 1
MRPS2 mitochondrial ribosomal protein S2
MUC2 mucin 2, oligomeric mucus/gel-forming
MXI1 MAX interactor 1, dimerization protein
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NR4A2 nuclear receptor subfamily 4, group A, member 2
RCAN1 regulator of calcineurin 1
RHOB ras homolog family member B
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila)
RUNX1 runt-related transcription factor 1
SCGB2A2 secretoglobin, family 2A, member 2
SERTAD2 SERTA domain containing 2
SLC26A3 solute carrier family 26 (anion exchanger), member 3
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5
SMC1A structural maintenance of chromosomes 1A
SPINK1 serine peptidase inhibitor, Kazal type 1
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINT1 serine peptidase inhibitor, Kunitz type 1
STAG3 stromal antigen 3
STC1 stanniocalcin 1
SULF1 sulfatase 1
TEX10 testis expressed 10
TFF3 trefoil factor 3 (intestinal)
THBS2 thrombospondin 2
TMEM30B transmembrane protein 30B
TRPS1 trichorhinophalangeal syndrome I
TSC22D3 TSC22 domain family, member 3
TTC39A tetratricopeptide repeat domain 39A
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF281 zinc finger protein 281
ZNF93 zinc finger protein 93

decreased expression

Symbol Name
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1A1 aldehyde dehydrogenase 1 family, member A1
ALDH1A2 aldehyde dehydrogenase 1 family, member A2
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
AMIGO2 adhesion molecule with Ig-like domain 2
AQP3 aquaporin 3 (Gill blood group)
ARPC1A actin related protein 2/3 complex, subunit 1A, 41kDa
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa
ATP5S ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)
BCHE butyrylcholinesterase
BEX1 brain expressed, X-linked 1
C7 complement component 7
CA12 carbonic anhydrase XII
CAPNS1 calpain, small subunit 1
CAPZA2 capping protein (actin filament) muscle Z-line, alpha 2
CCNA2 cyclin A2
CD24 CD24 molecule
CDC25B cell division cycle 25B
CDC42EP4 CDC42 effector protein (Rho GTPase binding) 4
CLU clusterin
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen)
CRIP2 cysteine-rich protein 2
CRYAB crystallin, alpha B
CST3 cystatin C
CTSH cathepsin H
CTSL cathepsin L
DEFB1 defensin, beta 1
DKK1 dickkopf WNT signaling pathway inhibitor 1
DLD dihydrolipoamide dehydrogenase
EIF1AY eukaryotic translation initiation factor 1A, Y-linked
EMP3 epithelial membrane protein 3
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FAM162A family with sequence similarity 162, member A
FGG fibrinogen gamma chain
FXYD2 FXYD domain containing ion transport regulator 2
GPI glucose-6-phosphate isomerase
GPX1 glutathione peroxidase 1
GPX2 glutathione peroxidase 2
GPX3 glutathione peroxidase 3
GSTO1 glutathione S-transferase omega 1
GTF2H5 general transcription factor IIH, polypeptide 5
GTPBP8 GTP-binding protein 8 (putative)
HBB hemoglobin, beta
HDDC2 HD domain containing 2
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IGFBP1 insulin-like growth factor binding protein 1
IGFBP4 insulin-like growth factor binding protein 4
ITGB5 integrin, beta 5
KCTD12 potassium channel tetramerization domain containing 12
KDM5D lysine (K)-specific demethylase 5D
KIAA0101 KIAA0101
KRT10 keratin 10, type I
KRT13 keratin 13, type I
KRT14 keratin 14, type I
KRT6A keratin 6A, type II
KRT6B keratin 6B, type II
KYNU kynureninase
LAMA5 laminin, alpha 5
LAMB1 laminin, beta 1
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LIG1 ligase I, DNA, ATP-dependent
LY6D lymphocyte antigen 6 complex, locus D
LYPLA1 lysophospholipase I
LYZ lysozyme
MATN2 matrilin 2
MET MET proto-oncogene, receptor tyrosine kinase
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
MYCBP MYC binding protein
NDRG2 NDRG family member 2
NR2F2 nuclear receptor subfamily 2, group F, member 2
NRCAM neuronal cell adhesion molecule
PALMD palmdelphin
PCBD1 pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
PGAM1 phosphoglycerate mutase 1 (brain)
PKM pyruvate kinase, muscle
PLAGL1 pleiomorphic adenoma gene-like 1
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRSS23 protease, serine, 23
PXMP2 peroxisomal membrane protein 2, 22kDa
RBP1 retinol binding protein 1, cellular
RIN2 Ras and Rab interactor 2
RNASET2 ribonuclease T2
RNF167 ring finger protein 167
S100A2 S100 calcium binding protein A2
S100A7 S100 calcium binding protein A7
S100A9 S100 calcium binding protein A9
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SFN stratifin
SFRP1 secreted frizzled-related protein 1
SLPI secretory leukocyte peptidase inhibitor
SPRR1A small proline-rich protein 1A
SRGN serglycin
STOM stomatin
STX1A syntaxin 1A (brain)
TCAF1 TRPM8 channel-associated factor 1
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TFPI2 tissue factor pathway inhibitor 2
TGFBI transforming growth factor, beta-induced, 68kDa
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TGM2 transglutaminase 2
THBD thrombomodulin
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TM4SF1 transmembrane 4 L six family member 1
TMEM5 transmembrane protein 5
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNPO1 transportin 1
TPM1 tropomyosin 1 (alpha)
TRIM16 tripartite motif containing 16
TSEN2 TSEN2 tRNA splicing endonuclease subunit
TSPAN3 tetraspanin 3
TUBB tubulin, beta class I
TUSC3 tumor suppressor candidate 3
UNC119B unc-119 homolog B (C. elegans)
URI1 URI1, prefoldin-like chaperone
VDAC1 voltage-dependent anion channel 1
WBSCR22 Williams Beuren syndrome chromosome region 22
WDR61 WD repeat domain 61