BRD-K84937637_A-275_HCC515_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

89 genes differentially expressed following the BRD-K84937637_A-275_HCC515_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
AGR2 anterior gradient 2
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
AMIGO2 adhesion molecule with Ig-like domain 2
ANXA1 annexin A1
CADM1 cell adhesion molecule 1
CAV1 caveolin 1, caveolae protein, 22kDa
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
DAPK1 death-associated protein kinase 1
DENND2D DENN/MADD domain containing 2D
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
EGR1 early growth response 1
FOLR1 folate receptor 1 (adult)
FSTL1 follistatin-like 1
GABARAPL1 GABA(A) receptor-associated protein like 1
GPX3 glutathione peroxidase 3
HEBP1 heme binding protein 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IGHMBP2 immunoglobulin mu binding protein 2
LTA4H leukotriene A4 hydrolase
LTF lactotransferrin
MET MET proto-oncogene, receptor tyrosine kinase
MGP matrix Gla protein
PLS3 plastin 3
RBM47 RNA binding motif protein 47
REXO2 RNA exonuclease 2
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
SLC16A4 solute carrier family 16, member 4
SRPX sushi-repeat containing protein, X-linked
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TSPAN13 tetraspanin 13
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
WIF1 WNT inhibitory factor 1

decreased expression

Symbol Name
ABHD2 abhydrolase domain containing 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ATP2A3 ATPase, Ca++ transporting, ubiquitous
BPTF bromodomain PHD finger transcription factor
CA2 carbonic anhydrase II
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5
CFB complement factor B
CPE carboxypeptidase E
DICER1 dicer 1, ribonuclease type III
DYRK2 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
EIF5 eukaryotic translation initiation factor 5
FAM63A family with sequence similarity 63, member A
FGF13 fibroblast growth factor 13
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGL2 fibrinogen-like 2
GPX2 glutathione peroxidase 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
IGF1 insulin-like growth factor 1 (somatomedin C)
ILF3 interleukin enhancer binding factor 3, 90kDa
IQGAP1 IQ motif containing GTPase activating protein 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LOC100505650 uncharacterized LOC100505650
MAN1A1 mannosidase, alpha, class 1A, member 1
MTSS1 metastasis suppressor 1
NCAM1 neural cell adhesion molecule 1
NKTR natural killer cell triggering receptor
NPY1R neuropeptide Y receptor Y1
PBX3 pre-B-cell leukemia homeobox 3
PI3 peptidase inhibitor 3, skin-derived
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
POLR1C polymerase (RNA) I polypeptide C, 30kDa
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform
PRKCI protein kinase C, iota
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRD protein tyrosine phosphatase, receptor type, D
RHOBTB3 Rho-related BTB domain containing 3
SCARB2 scavenger receptor class B, member 2
SDC1 syndecan 1
SDC2 syndecan 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SF3B1 splicing factor 3b, subunit 1, 155kDa
SNAI2 snail family zinc finger 2
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYT1 synaptotagmin I
TFRC transferrin receptor
TMEM158 transmembrane protein 158 (gene/pseudogene)
TOX3 TOX high mobility group box family member 3
TUBB2A tubulin, beta 2A class IIa
USP1 ubiquitin specific peptidase 1