BRD-K84987553_-666_HT29_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

54 genes differentially expressed following the BRD-K84987553_-666_HT29_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABHD4 abhydrolase domain containing 4
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
AKR1C3 aldo-keto reductase family 1, member C3
ALDH3A1 aldehyde dehydrogenase 3 family, member A1
BAG3 BCL2-associated athanogene 3
CBR1 carbonyl reductase 1
CBR3 carbonyl reductase 3
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CTSL cathepsin L
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic)
FTH1 ferritin, heavy polypeptide 1
G6PD glucose-6-phosphate dehydrogenase
GCLM glutamate-cysteine ligase, modifier subunit
HMOX1 heme oxygenase 1
HPRT1 hypoxanthine phosphoribosyltransferase 1
HSPH1 heat shock 105kDa/110kDa protein 1
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
NQO1 NAD(P)H dehydrogenase, quinone 1
NTRK2 neurotrophic tyrosine kinase, receptor, type 2
PGD phosphogluconate dehydrogenase
PHLDA1 pleckstrin homology-like domain, family A, member 1
PIR pirin (iron-binding nuclear protein)
PTX3 pentraxin 3, long
RAP1GAP RAP1 GTPase activating protein
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SNX11 sorting nexin 11
SQSTM1 sequestosome 1
TRIM16 tripartite motif containing 16
TXN thioredoxin
TXNRD1 thioredoxin reductase 1
UGDH UDP-glucose 6-dehydrogenase

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
BLNK B-cell linker
CPE carboxypeptidase E
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5
FHL1 four and a half LIM domains 1
GPM6B glycoprotein M6B
KLK5 kallikrein-related peptidase 5
PDZD2 PDZ domain containing 2
PEG10 paternally expressed 10
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5
RELN reelin
RGS2 regulator of G-protein signaling 2
RHOB ras homolog family member B
SEPP1 selenoprotein P, plasma, 1
SPON1 spondin 1, extracellular matrix protein
THBS2 thrombospondin 2
VTCN1 V-set domain containing T cell activation inhibitor 1
XIST X inactive specific transcript (non-protein coding)
Funding