BRD-K85119730_-666_A375_6.0_h_10.0_um Gene Set
Genes
49 genes differentially expressed following the BRD-K85119730_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
Symbol |
Name |
ABLIM1
|
actin binding LIM protein 1
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
ALDH3A2
|
aldehyde dehydrogenase 3 family, member A2
|
BCL6
|
B-cell CLL/lymphoma 6
|
CCL5
|
chemokine (C-C motif) ligand 5
|
CD36
|
CD36 molecule (thrombospondin receptor)
|
CEBPD
|
CCAAT/enhancer binding protein (C/EBP), delta
|
CITED2
|
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
|
CSTA
|
cystatin A (stefin A)
|
EFEMP1
|
EGF containing fibulin-like extracellular matrix protein 1
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
HOPX
|
HOP homeobox
|
IFITM1
|
interferon induced transmembrane protein 1
|
IFITM2
|
interferon induced transmembrane protein 2
|
IFITM3
|
interferon induced transmembrane protein 3
|
LIPG
|
lipase, endothelial
|
MYOF
|
myoferlin
|
NR2F1
|
nuclear receptor subfamily 2, group F, member 1
|
PLCB1
|
phospholipase C, beta 1 (phosphoinositide-specific)
|
PRF1
|
perforin 1 (pore forming protein)
|
RBP1
|
retinol binding protein 1, cellular
|
S100A8
|
S100 calcium binding protein A8
|
SLAMF1
|
signaling lymphocytic activation molecule family member 1
|
SOX11
|
SRY (sex determining region Y)-box 11
|
SPINK2
|
serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
|
TCF7L2
|
transcription factor 7-like 2 (T-cell specific, HMG-box)
|
decreased expression
Symbol |
Name |
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
ACP5
|
acid phosphatase 5, tartrate resistant
|
ALOX5
|
arachidonate 5-lipoxygenase
|
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
|
CKS2
|
CDC28 protein kinase regulatory subunit 2
|
COL8A2
|
collagen, type VIII, alpha 2
|
CPE
|
carboxypeptidase E
|
CXCL14
|
chemokine (C-X-C motif) ligand 14
|
GREM1
|
gremlin 1, DAN family BMP antagonist
|
INSR
|
insulin receptor
|
ITM2C
|
integral membrane protein 2C
|
LXN
|
latexin
|
MAN1A1
|
mannosidase, alpha, class 1A, member 1
|
MECOM
|
MDS1 and EVI1 complex locus
|
MMP9
|
matrix metallopeptidase 9
|
SDC1
|
syndecan 1
|
SH3BGRL
|
SH3 domain binding glutamate-rich protein like
|
SLC20A1
|
solute carrier family 20 (phosphate transporter), member 1
|
TBC1D9
|
TBC1 domain family, member 9 (with GRAM domain)
|
TBL1XR1
|
transducin (beta)-like 1 X-linked receptor 1
|
TSPYL5
|
TSPY-like 5
|
TUBA4A
|
tubulin, alpha 4a
|
UQCRH
|
ubiquinol-cytochrome c reductase hinge protein
|