BRD-K85119730_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

49 genes differentially expressed following the BRD-K85119730_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM1 actin binding LIM protein 1
ADO 2-aminoethanethiol (cysteamine) dioxygenase
ALDH3A2 aldehyde dehydrogenase 3 family, member A2
BCL6 B-cell CLL/lymphoma 6
CCL5 chemokine (C-C motif) ligand 5
CD36 CD36 molecule (thrombospondin receptor)
CEBPD CCAAT/enhancer binding protein (C/EBP), delta
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CSTA cystatin A (stefin A)
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1
FABP5 fatty acid binding protein 5 (psoriasis-associated)
HOPX HOP homeobox
IFITM1 interferon induced transmembrane protein 1
IFITM2 interferon induced transmembrane protein 2
IFITM3 interferon induced transmembrane protein 3
LIPG lipase, endothelial
MYOF myoferlin
NR2F1 nuclear receptor subfamily 2, group F, member 1
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PRF1 perforin 1 (pore forming protein)
RBP1 retinol binding protein 1, cellular
S100A8 S100 calcium binding protein A8
SLAMF1 signaling lymphocytic activation molecule family member 1
SOX11 SRY (sex determining region Y)-box 11
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACP5 acid phosphatase 5, tartrate resistant
ALOX5 arachidonate 5-lipoxygenase
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
CKS2 CDC28 protein kinase regulatory subunit 2
COL8A2 collagen, type VIII, alpha 2
CPE carboxypeptidase E
CXCL14 chemokine (C-X-C motif) ligand 14
GREM1 gremlin 1, DAN family BMP antagonist
INSR insulin receptor
ITM2C integral membrane protein 2C
LXN latexin
MAN1A1 mannosidase, alpha, class 1A, member 1
MECOM MDS1 and EVI1 complex locus
MMP9 matrix metallopeptidase 9
SDC1 syndecan 1
SH3BGRL SH3 domain binding glutamate-rich protein like
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
TBC1D9 TBC1 domain family, member 9 (with GRAM domain)
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TSPYL5 TSPY-like 5
TUBA4A tubulin, alpha 4a
UQCRH ubiquinol-cytochrome c reductase hinge protein