| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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105 genes differentially expressed following the BRD-K85402309_dovitinib_HEPG2_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AARS | alanyl-tRNA synthetase |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ATF4 | activating transcription factor 4 |
| BBX | bobby sox homolog (Drosophila) |
| BCL6 | B-cell CLL/lymphoma 6 |
| BPIFA1 | BPI fold containing family A, member 1 |
| C5AR1 | complement component 5a receptor 1 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CARS | cysteinyl-tRNA synthetase |
| CBS | cystathionine-beta-synthase |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta |
| CSTA | cystatin A (stefin A) |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DOCK4 | dedicator of cytokinesis 4 |
| EIF4EBP1 | eukaryotic translation initiation factor 4E binding protein 1 |
| EPRS | glutamyl-prolyl-tRNA synthetase |
| ERBB3 | erb-b2 receptor tyrosine kinase 3 |
| GARS | glycyl-tRNA synthetase |
| GAS1 | growth arrest-specific 1 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HIST1H2AC | histone cluster 1, H2ac |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| INHBA | inhibin, beta A |
| KRT7 | keratin 7, type II |
| KYNU | kynureninase |
| MT1F | metallothionein 1F |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase |
| MYO10 | myosin X |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PHGDH | phosphoglycerate dehydrogenase |
| RAB31 | RAB31, member RAS oncogene family |
| S100P | S100 calcium binding protein P |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SHMT2 | serine hydroxymethyltransferase 2 (mitochondrial) |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SPG20 | spastic paraplegia 20 (Troyer syndrome) |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TGM2 | transglutaminase 2 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 |
| TWF2 | twinfilin actin binding protein 2 |
| VLDLR | very low density lipoprotein receptor |
| WWOX | WW domain containing oxidoreductase |
| YARS | tyrosyl-tRNA synthetase |
| ZNF652 | zinc finger protein 652 |
| Symbol | Name |
|---|---|
| BIRC5 | baculoviral IAP repeat containing 5 |
| CA12 | carbonic anhydrase XII |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CDC20 | cell division cycle 20 |
| CDK1 | cyclin-dependent kinase 1 |
| CENPE | centromere protein E, 312kDa |
| CHEK2 | checkpoint kinase 2 |
| CLTB | clathrin, light chain B |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COPS7A | COP9 signalosome subunit 7A |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CST6 | cystatin E/M |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
| FABP7 | fatty acid binding protein 7, brain |
| GAL | galanin/GMAP prepropeptide |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| H2AFX | H2A histone family, member X |
| HMGCR | 3-hydroxy-3-methylglutaryl-CoA reductase |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| KIF20A | kinesin family member 20A |
| LRRC17 | leucine rich repeat containing 17 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| MATN2 | matrilin 2 |
| MCM10 | minichromosome maintenance complex component 10 |
| MSMO1 | methylsterol monooxygenase 1 |
| NPTX1 | neuronal pentraxin I |
| PLK1 | polo-like kinase 1 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| S100A10 | S100 calcium binding protein A10 |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SPARCL1 | SPARC-like 1 (hevin) |
| STMN1 | stathmin 1 |
| TUBB3 | tubulin, beta 3 class III |
| TUBB4B | tubulin, beta 4B class IVb |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| XIST | X inactive specific transcript (non-protein coding) |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| ZWINT | ZW10 interacting kinetochore protein |
