Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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81 genes differentially expressed following the BRD-K85402309_dovitinib_HS578T_3_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 |
AQP3 | aquaporin 3 (Gill blood group) |
BAMBI | BMP and activin membrane-bound inhibitor |
C7 | complement component 7 |
CADM1 | cell adhesion molecule 1 |
CCND2 | cyclin D2 |
DDIT4 | DNA-damage-inducible transcript 4 |
DEPTOR | DEP domain containing MTOR-interacting protein |
DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 |
EHD3 | EH-domain containing 3 |
EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) |
GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 |
IGFBP5 | insulin-like growth factor binding protein 5 |
IL1R1 | interleukin 1 receptor, type I |
ITM2A | integral membrane protein 2A |
KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 |
LOC100505650 | uncharacterized LOC100505650 |
MPZL2 | myelin protein zero-like 2 |
NCALD | neurocalcin delta |
PPL | periplakin |
PTCH1 | patched 1 |
QPCT | glutaminyl-peptide cyclotransferase |
RBKS | ribokinase |
RRAGD | Ras-related GTP binding D |
SNAP25 | synaptosomal-associated protein, 25kDa |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
VLDLR | very low density lipoprotein receptor |
WFDC1 | WAP four-disulfide core domain 1 |
WNT5A | wingless-type MMTV integration site family, member 5A |
ZNF586 | zinc finger protein 586 |
Symbol | Name |
---|---|
ADIRF | adipogenesis regulatory factor |
AREG | amphiregulin |
ARL4C | ADP-ribosylation factor-like 4C |
ARMCX2 | armadillo repeat containing, X-linked 2 |
AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
CCL2 | chemokine (C-C motif) ligand 2 |
CCND1 | cyclin D1 |
CD14 | CD14 molecule |
CREB1 | cAMP responsive element binding protein 1 |
CXCL10 | chemokine (C-X-C motif) ligand 10 |
CXCL8 | chemokine (C-X-C motif) ligand 8 |
DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
DUSP6 | dual specificity phosphatase 6 |
EFNB2 | ephrin-B2 |
EGR3 | early growth response 3 |
FABP4 | fatty acid binding protein 4, adipocyte |
FOSL1 | FOS-like antigen 1 |
GEM | GTP binding protein overexpressed in skeletal muscle |
GLIPR1 | GLI pathogenesis-related 1 |
HBEGF | heparin-binding EGF-like growth factor |
HMGA2 | high mobility group AT-hook 2 |
IER3 | immediate early response 3 |
IL13RA2 | interleukin 13 receptor, alpha 2 |
ISG15 | ISG15 ubiquitin-like modifier |
ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
LAMB3 | laminin, beta 3 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
LTF | lactotransferrin |
MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 |
MAPT | microtubule-associated protein tau |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
MMP9 | matrix metallopeptidase 9 |
PAN2 | PAN2 poly(A) specific ribonuclease subunit |
PEG10 | paternally expressed 10 |
PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
PIP | prolactin-induced protein |
PLAUR | plasminogen activator, urokinase receptor |
PTX3 | pentraxin 3, long |
RCAN1 | regulator of calcineurin 1 |
SEPP1 | selenoprotein P, plasma, 1 |
SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) |
SOX11 | SRY (sex determining region Y)-box 11 |
SOX9 | SRY (sex determining region Y)-box 9 |
TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
TFF1 | trefoil factor 1 |
TLR4 | toll-like receptor 4 |