| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
60 genes differentially expressed following the BRD-K85606544_neratinib_BT20_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACKR3 | atypical chemokine receptor 3 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FRZB | frizzled-related protein |
| GBP1 | guanylate binding protein 1, interferon-inducible |
| GLUL | glutamate-ammonia ligase |
| GPX3 | glutathione peroxidase 3 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| IFI27 | interferon, alpha-inducible protein 27 |
| ITM2A | integral membrane protein 2A |
| JUN | jun proto-oncogene |
| LCN2 | lipocalin 2 |
| LEFTY1 | left-right determination factor 1 |
| MECOM | MDS1 and EVI1 complex locus |
| MFAP5 | microfibrillar associated protein 5 |
| MUC4 | mucin 4, cell surface associated |
| NKG7 | natural killer cell granule protein 7 |
| PCDH7 | protocadherin 7 |
| SELENBP1 | selenium binding protein 1 |
| SLC38A2 | solute carrier family 38, member 2 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| TSC22D3 | TSC22 domain family, member 3 |
| VAT1 | vesicle amine transport 1 |
| WARS | tryptophanyl-tRNA synthetase |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |
| Symbol | Name |
|---|---|
| ABHD2 | abhydrolase domain containing 2 |
| ADCY1 | adenylate cyclase 1 (brain) |
| ANPEP | alanyl (membrane) aminopeptidase |
| ANXA5 | annexin A5 |
| CTGF | connective tissue growth factor |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DUSP4 | dual specificity phosphatase 4 |
| EGR3 | early growth response 3 |
| FOSL1 | FOS-like antigen 1 |
| HBEGF | heparin-binding EGF-like growth factor |
| IER3 | immediate early response 3 |
| MGP | matrix Gla protein |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| POSTN | periostin, osteoblast specific factor |
| PSPH | phosphoserine phosphatase |
| QPCT | glutaminyl-peptide cyclotransferase |
| RGS10 | regulator of G-protein signaling 10 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| SFRP1 | secreted frizzled-related protein 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPP1 | secreted phosphoprotein 1 |
| SRGN | serglycin |
| SRPX | sushi-repeat containing protein, X-linked |
| THBS1 | thrombospondin 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| VAMP8 | vesicle-associated membrane protein 8 |
