| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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67 genes differentially expressed following the BRD-K85606544_neratinib_MCF7_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADM | adrenomedullin |
| CP | ceruloplasmin (ferroxidase) |
| DEFB1 | defensin, beta 1 |
| ETV5 | ets variant 5 |
| FGB | fibrinogen beta chain |
| GLS | glutaminase |
| HMOX1 | heme oxygenase 1 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
| KLF6 | Kruppel-like factor 6 |
| LBP | lipopolysaccharide binding protein |
| LCN2 | lipocalin 2 |
| MT1X | metallothionein 1X |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| SATB1 | SATB homeobox 1 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SLC37A4 | solute carrier family 37 (glucose-6-phosphate transporter), member 4 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) |
| STEAP3 | STEAP family member 3, metalloreductase |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TPP1 | tripeptidyl peptidase I |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VAMP8 | vesicle-associated membrane protein 8 |
| Symbol | Name |
|---|---|
| AGR2 | anterior gradient 2 |
| AIM1 | absent in melanoma 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CFH | complement factor H |
| COL14A1 | collagen, type XIV, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| CPM | carboxypeptidase M |
| CTSC | cathepsin C |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 |
| EVL | Enah/Vasp-like |
| FAM198B | family with sequence similarity 198, member B |
| FBN1 | fibrillin 1 |
| FHL1 | four and a half LIM domains 1 |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| LOXL1 | lysyl oxidase-like 1 |
| LRRC17 | leucine rich repeat containing 17 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MREG | melanoregulin |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PALLD | palladin, cytoskeletal associated protein |
| PDLIM3 | PDZ and LIM domain 3 |
| PLAT | plasminogen activator, tissue |
| PLN | phospholamban |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 |
| RAB38 | RAB38, member RAS oncogene family |
| RGS5 | regulator of G-protein signaling 5 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RRM2 | ribonucleotide reductase M2 |
| S100P | S100 calcium binding protein P |
| SDC2 | syndecan 2 |
| SORD | sorbitol dehydrogenase |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) |
| TFF1 | trefoil factor 1 |
| TLR4 | toll-like receptor 4 |
| TSPAN4 | tetraspanin 4 |
| VCAN | versican |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| WWTR1 | WW domain containing transcription regulator 1 |
| XIST | X inactive specific transcript (non-protein coding) |
