BRD-K86456986_5,7-difluoro-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one KLK-46_PC3_6.0_h_10.0_um Gene Set
Genes
50 genes differentially expressed following the BRD-K86456986_5,7-difluoro-6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indol-1-one KLK-46_PC3_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
increased expression
| Symbol |
Name |
|
1060P11.3
|
killer cell immunoglobulin-like receptor, three domains, pseudogene
|
|
CCNG2
|
cyclin G2
|
|
ENPP1
|
ectonucleotide pyrophosphatase/phosphodiesterase 1
|
|
ESR1
|
estrogen receptor 1
|
|
GMPR
|
guanosine monophosphate reductase
|
|
IFI6
|
interferon, alpha-inducible protein 6
|
|
IGHD
|
immunoglobulin heavy constant delta
|
|
IGHM
|
immunoglobulin heavy constant mu
|
|
IGKV1-5
|
immunoglobulin kappa variable 1-5
|
|
IGKV3-20
|
immunoglobulin kappa variable 3-20
|
|
IGKV4-1
|
immunoglobulin kappa variable 4-1
|
|
KRT14
|
keratin 14, type I
|
|
KRT23
|
keratin 23, type I
|
|
LDOC1
|
leucine zipper, down-regulated in cancer 1
|
|
NOTCH2NL
|
notch 2 N-terminal like
|
|
RBP4
|
retinol binding protein 4, plasma
|
|
SCUBE2
|
signal peptide, CUB domain, EGF-like 2
|
|
STC2
|
stanniocalcin 2
|
|
TBL1X
|
transducin (beta)-like 1X-linked
|
|
TFAP2A
|
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
|
|
TRPS1
|
trichorhinophalangeal syndrome I
|
|
TTC39A
|
tetratricopeptide repeat domain 39A
|
|
TXNIP
|
thioredoxin interacting protein
|
|
VCAM1
|
vascular cell adhesion molecule 1
|
|
XYLT1
|
xylosyltransferase I
|
|
ZBTB20
|
zinc finger and BTB domain containing 20
|
decreased expression
| Symbol |
Name |
|
ADI1
|
acireductone dioxygenase 1
|
|
APLP2
|
amyloid beta (A4) precursor-like protein 2
|
|
AQP3
|
aquaporin 3 (Gill blood group)
|
|
ARF4
|
ADP-ribosylation factor 4
|
|
CALB1
|
calbindin 1, 28kDa
|
|
CANX
|
calnexin
|
|
CLTC
|
clathrin, heavy chain (Hc)
|
|
CTSH
|
cathepsin H
|
|
CXCL8
|
chemokine (C-X-C motif) ligand 8
|
|
DST
|
dystonin
|
|
ENPP2
|
ectonucleotide pyrophosphatase/phosphodiesterase 2
|
|
FASTKD5
|
FAST kinase domains 5
|
|
GPRC5A
|
G protein-coupled receptor, class C, group 5, member A
|
|
HSP90B1
|
heat shock protein 90kDa beta (Grp94), member 1
|
|
IPO5
|
importin 5
|
|
MSH6
|
mutS homolog 6
|
|
PGK1
|
phosphoglycerate kinase 1
|
|
PSPH
|
phosphoserine phosphatase
|
|
S100A7
|
S100 calcium binding protein A7
|
|
SFRP1
|
secreted frizzled-related protein 1
|
|
TCN1
|
transcobalamin I (vitamin B12 binding protein, R binder family)
|
|
TFRC
|
transferrin receptor
|
|
TMEM47
|
transmembrane protein 47
|
|
UBE2A
|
ubiquitin-conjugating enzyme E2A
|
