BRD-K86472598_-666_MCF7_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

64 genes differentially expressed following the BRD-K86472598_-666_MCF7_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABHD4 abhydrolase domain containing 4
APOC1 apolipoprotein C-I
ASNS asparagine synthetase (glutamine-hydrolyzing)
AZU1 azurocidin 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHIC2 cysteine-rich hydrophobic domain 2
CLU clusterin
CTSG cathepsin G
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DUSP5 dual specificity phosphatase 5
ELANE elastase, neutrophil expressed
FN1 fibronectin 1
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 FOS-like antigen 1
FTH1 ferritin, heavy polypeptide 1
GADD45A growth arrest and DNA-damage-inducible, alpha
GMFG glia maturation factor, gamma
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
HSPH1 heat shock 105kDa/110kDa protein 1
IER5 immediate early response 5
IFRD1 interferon-related developmental regulator 1
JUN jun proto-oncogene
MPO myeloperoxidase
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PSAT1 phosphoserine aminotransferase 1
SESN1 sestrin 1
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
STAR steroidogenic acute regulatory protein
TRIB1 tribbles pseudokinase 1
TXNRD1 thioredoxin reductase 1
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

decreased expression

Symbol Name
ATF5 activating transcription factor 5
AZGP1 alpha-2-glycoprotein 1, zinc-binding
B3GNT1
BCHE butyrylcholinesterase
BDH1 3-hydroxybutyrate dehydrogenase, type 1
CANT1 calcium activated nucleotidase 1
CDC20 cell division cycle 20
ERBB3 erb-b2 receptor tyrosine kinase 3
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6
GPD1L glycerol-3-phosphate dehydrogenase 1-like
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
MARCKS myristoylated alanine-rich protein kinase C substrate
MREG melanoregulin
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NREP neuronal regeneration related protein
PLK1 polo-like kinase 1
PRR7 proline rich 7 (synaptic)
SFRP1 secreted frizzled-related protein 1
SMAD3 SMAD family member 3
SOX4 SRY (sex determining region Y)-box 4
SPDEF SAM pointed domain containing ETS transcription factor
TFF1 trefoil factor 1
TGFBR3 transforming growth factor, beta receptor III
VGLL4 vestigial-like family member 4
ZMIZ1 zinc finger, MIZ-type containing 1