BRD-K86574132_-666_A375_6.0_h_48.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

12 genes differentially expressed following the BRD-K86574132_-666_A375_6.0_h_48.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLC Charcot-Leyden crystal galectin
DDIT4 DNA-damage-inducible transcript 4
FHL1 four and a half LIM domains 1
GADD45A growth arrest and DNA-damage-inducible, alpha
HMOX1 heme oxygenase 1
IGFBP5 insulin-like growth factor binding protein 5
S100P S100 calcium binding protein P

decreased expression

Symbol Name
CCNF cyclin F
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
SACS sacsin molecular chaperone
Funding