Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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54 genes differentially expressed following the BRD-K86797399_pracinostat_A549_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AHNAK2 | AHNAK nucleoprotein 2 |
AQP3 | aquaporin 3 (Gill blood group) |
CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
EFNA1 | ephrin-A1 |
FEZ2 | fasciculation and elongation protein zeta 2 (zygin II) |
FOXO4 | forkhead box O4 |
GPRC5A | G protein-coupled receptor, class C, group 5, member A |
IFI6 | interferon, alpha-inducible protein 6 |
IGF2R | insulin-like growth factor 2 receptor |
IGFBP5 | insulin-like growth factor binding protein 5 |
L1CAM | L1 cell adhesion molecule |
LAPTM4B | lysosomal protein transmembrane 4 beta |
LGALS1 | lectin, galactoside-binding, soluble, 1 |
LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein |
MATN2 | matrilin 2 |
MT1X | metallothionein 1X |
MT2A | metallothionein 2A |
NEFL | neurofilament, light polypeptide |
PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) |
PCSK1 | proprotein convertase subtilisin/kexin type 1 |
PEG10 | paternally expressed 10 |
PEG3 | paternally expressed 3 |
PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
SGCE | sarcoglycan, epsilon |
SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
THBS1 | thrombospondin 1 |
TNNT1 | troponin T type 1 (skeletal, slow) |
UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
Symbol | Name |
---|---|
AEBP1 | AE binding protein 1 |
CXCL9 | chemokine (C-X-C motif) ligand 9 |
GREM1 | gremlin 1, DAN family BMP antagonist |
HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
HOXA5 | homeobox A5 |
HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
KRT5 | keratin 5, type II |
LTF | lactotransferrin |
LYN | LYN proto-oncogene, Src family tyrosine kinase |
ODC1 | ornithine decarboxylase 1 |
PHF11 | PHD finger protein 11 |
PRAME | preferentially expressed antigen in melanoma |
PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 |
RCC1 | regulator of chromosome condensation 1 |
RGCC | regulator of cell cycle |
RSL1D1 | ribosomal L1 domain containing 1 |
S100A7 | S100 calcium binding protein A7 |
S100A9 | S100 calcium binding protein A9 |
SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 |
SPRR1A | small proline-rich protein 1A |
SPRR3 | small proline-rich protein 3 |
TWIST1 | twist family bHLH transcription factor 1 |