| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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297 genes differentially expressed following the BRD-K86797399_pracinostat_A549_24_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 |
| ADIRF | adipogenesis regulatory factor |
| AHR | aryl hydrocarbon receptor |
| ALDOB | aldolase B, fructose-bisphosphate |
| ALDOC | aldolase C, fructose-bisphosphate |
| APLP2 | amyloid beta (A4) precursor-like protein 2 |
| AREG | amphiregulin |
| ARG2 | arginase 2 |
| ATF3 | activating transcription factor 3 |
| BBOX1 | butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 |
| BLNK | B-cell linker |
| BTBD3 | BTB (POZ) domain containing 3 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) |
| CBLB | Cbl proto-oncogene B, E3 ubiquitin protein ligase |
| CCNA1 | cyclin A1 |
| CD36 | CD36 molecule (thrombospondin receptor) |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CD9 | CD9 molecule |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CDKN2A | cyclin-dependent kinase inhibitor 2A |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CFD | complement factor D (adipsin) |
| CHGB | chromogranin B |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLTB | clathrin, light chain B |
| COL1A1 | collagen, type I, alpha 1 |
| COL6A3 | collagen, type VI, alpha 3 |
| CPVL | carboxypeptidase, vitellogenic-like |
| CSTA | cystatin A (stefin A) |
| CTSB | cathepsin B |
| CYB5R1 | cytochrome b5 reductase 1 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 |
| DNM3 | dynamin 3 |
| DUSP14 | dual specificity phosphatase 14 |
| EFNA1 | ephrin-A1 |
| EZR | ezrin |
| F11R | F11 receptor |
| FADS3 | fatty acid desaturase 3 |
| FAM117A | family with sequence similarity 117, member A |
| FAXDC2 | fatty acid hydroxylase domain containing 2 |
| FBXO2 | F-box protein 2 |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FOLR1 | folate receptor 1 (adult) |
| FOXO4 | forkhead box O4 |
| FUCA1 | fucosidase, alpha-L- 1, tissue |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 |
| GLS | glutaminase |
| GM2A | GM2 ganglioside activator |
| GNAI2 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GOLGA8A | golgin A8 family, member A |
| GPR137B | G protein-coupled receptor 137B |
| GPX3 | glutathione peroxidase 3 |
| GRAMD3 | GRAM domain containing 3 |
| GRN | granulin |
| GSTA1 | glutathione S-transferase alpha 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HDAC5 | histone deacetylase 5 |
| HEBP1 | heme binding protein 1 |
| HECA | headcase homolog (Drosophila) |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST1H3H | histone cluster 1, H3h |
| HK1 | hexokinase 1 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGF2R | insulin-like growth factor 2 receptor |
| INPP1 | inositol polyphosphate-1-phosphatase |
| INSR | insulin receptor |
| ISG15 | ISG15 ubiquitin-like modifier |
| L1CAM | L1 cell adhesion molecule |
| LIPA | lipase A, lysosomal acid, cholesterol esterase |
| MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 |
| MAOB | monoamine oxidase B |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MIR22HG | MIR22 host gene |
| MLF1 | myeloid leukemia factor 1 |
| MT1X | metallothionein 1X |
| MXI1 | MAX interactor 1, dimerization protein |
| NCAM1 | neural cell adhesion molecule 1 |
| NDNF | neuron-derived neurotrophic factor |
| NDRG1 | N-myc downstream regulated 1 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NFIL3 | nuclear factor, interleukin 3 regulated |
| NOSIP | nitric oxide synthase interacting protein |
| NPC1 | Niemann-Pick disease, type C1 |
| OAT | ornithine aminotransferase |
| ORMDL2 | ORMDL sphingolipid biosynthesis regulator 2 |
| PBXIP1 | pre-B-cell leukemia homeobox interacting protein 1 |
| PCMT1 | protein-L-isoaspartate (D-aspartate) O-methyltransferase |
| PEG10 | paternally expressed 10 |
| PEG3 | paternally expressed 3 |
| PIEZO2 | piezo-type mechanosensitive ion channel component 2 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta |
| PLA2G15 | phospholipase A2, group XV |
| POR | P450 (cytochrome) oxidoreductase |
| PRSS2 | protease, serine, 2 (trypsin 2) |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RBKS | ribokinase |
| RCAN1 | regulator of calcineurin 1 |
| RGS10 | regulator of G-protein signaling 10 |
| RHOA | ras homolog family member A |
| RHOF | ras homolog family member F (in filopodia) |
| RIOK3 | RIO kinase 3 |
| RTN2 | reticulon 2 |
| SARAF | store-operated calcium entry-associated regulatory factor |
| SCPEP1 | serine carboxypeptidase 1 |
| SERINC3 | serine incorporator 3 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFXN3 | sideroflexin 3 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SMPDL3A | sphingomyelin phosphodiesterase, acid-like 3A |
| SORT1 | sortilin 1 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 |
| SPTLC2 | serine palmitoyltransferase, long chain base subunit 2 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SST | somatostatin |
| STAR | steroidogenic acute regulatory protein |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TCTA | T-cell leukemia translocation altered |
| TES | testin LIM domain protein |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TMC6 | transmembrane channel-like 6 |
| TPP1 | tripeptidyl peptidase I |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
| VAMP8 | vesicle-associated membrane protein 8 |
| VAT1 | vesicle amine transport 1 |
| VNN1 | vanin 1 |
| WDTC1 | WD and tetratricopeptide repeats 1 |
| YPEL5 | yippee-like 5 (Drosophila) |
| Symbol | Name |
|---|---|
| ADI1 | acireductone dioxygenase 1 |
| ADM | adrenomedullin |
| AGR2 | anterior gradient 2 |
| AK4 | adenylate kinase 4 |
| AKAP8 | A kinase (PRKA) anchor protein 8 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B |
| APOBEC3A | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATF5 | activating transcription factor 5 |
| AURKA | aurora kinase A |
| CA12 | carbonic anhydrase XII |
| CBR3 | carbonyl reductase 3 |
| CCL2 | chemokine (C-C motif) ligand 2 |
| CCNA2 | cyclin A2 |
| CD99 | CD99 molecule |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDK1 | cyclin-dependent kinase 1 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CENPA | centromere protein A |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL4A6 | collagen, type IV, alpha 6 |
| COL5A2 | collagen, type V, alpha 2 |
| CTBP1 | C-terminal binding protein 1 |
| CXCL10 | chemokine (C-X-C motif) ligand 10 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| DEPDC1 | DEP domain containing 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DPT | dermatopontin |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| EDN1 | endothelin 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EMP3 | epithelial membrane protein 3 |
| EXO1 | exonuclease 1 |
| FAM129A | family with sequence similarity 129, member A |
| FANCI | Fanconi anemia, complementation group I |
| FGFR3 | fibroblast growth factor receptor 3 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FOSL1 | FOS-like antigen 1 |
| FOXM1 | forkhead box M1 |
| GAL | galanin/GMAP prepropeptide |
| GALNT12 | polypeptide N-acetylgalactosaminyltransferase 12 |
| GALNT7 | polypeptide N-acetylgalactosaminyltransferase 7 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GINS3 | GINS complex subunit 3 (Psf3 homolog) |
| GOLM1 | golgi membrane protein 1 |
| GSAP | gamma-secretase activating protein |
| GTSE1 | G-2 and S-phase expressed 1 |
| HDDC2 | HD domain containing 2 |
| HDGFRP3 | hepatoma-derived growth factor, related protein 3 |
| HJURP | Holliday junction recognition protein |
| HMGA2 | high mobility group AT-hook 2 |
| HMGB1 | high mobility group box 1 |
| HMGB2 | high mobility group box 2 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 |
| IDO1 | indoleamine 2,3-dioxygenase 1 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IGLV3-19 | immunoglobulin lambda variable 3-19 |
| IPO5 | importin 5 |
| ITGB5 | integrin, beta 5 |
| KDM5D | lysine (K)-specific demethylase 5D |
| KIAA0368 | KIAA0368 |
| KIF11 | kinesin family member 11 |
| KIF18B | kinesin family member 18B |
| KIF20A | kinesin family member 20A |
| KIF4A | kinesin family member 4A |
| KLK11 | kallikrein-related peptidase 11 |
| LHX2 | LIM homeobox 2 |
| LMNB1 | lamin B1 |
| LMNB2 | lamin B2 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LRRC41 | leucine rich repeat containing 41 |
| LTF | lactotransferrin |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) |
| MCM2 | minichromosome maintenance complex component 2 |
| MCM3 | minichromosome maintenance complex component 3 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MDK | midkine (neurite growth-promoting factor 2) |
| MEIS2 | Meis homeobox 2 |
| MLPH | melanophilin |
| MOXD1 | monooxygenase, DBH-like 1 |
| MRPL15 | mitochondrial ribosomal protein L15 |
| MTERF3 | mitochondrial transcription termination factor 3 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming |
| NAMPT | nicotinamide phosphoribosyltransferase |
| NBN | nibrin |
| NCAPG | non-SMC condensin I complex, subunit G |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) |
| NME4 | NME/NM23 nucleoside diphosphate kinase 4 |
| NRN1 | neuritin 1 |
| NSMAF | neutral sphingomyelinase (N-SMase) activation associated factor |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase |
| PAIP1 | poly(A) binding protein interacting protein 1 |
| PARVB | parvin, beta |
| PAX6 | paired box 6 |
| PBK | PDZ binding kinase |
| PFAS | phosphoribosylformylglycinamidine synthase |
| PGD | phosphogluconate dehydrogenase |
| PHF11 | PHD finger protein 11 |
| PLBD1 | phospholipase B domain containing 1 |
| PNN | pinin, desmosome associated protein |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRC1 | protein regulator of cytokinesis 1 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RCN1 | reticulocalbin 1, EF-hand calcium binding domain |
| RFC3 | replication factor C (activator 1) 3, 38kDa |
| RGS2 | regulator of G-protein signaling 2 |
| RPIA | ribose 5-phosphate isomerase A |
| S100A12 | S100 calcium binding protein A12 |
| S100A7 | S100 calcium binding protein A7 |
| SCUBE2 | signal peptide, CUB domain, EGF-like 2 |
| SENP6 | SUMO1/sentrin specific peptidase 6 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 |
| SORBS3 | sorbin and SH3 domain containing 3 |
| SPAG7 | sperm associated antigen 7 |
| SPC25 | SPC25, NDC80 kinetochore complex component |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 |
| TP53 | tumor protein p53 |
| TRD | T cell receptor delta locus |
| TRIP13 | thyroid hormone receptor interactor 13 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TTN | titin |
| TUBB6 | tubulin, beta 6 class V |
| TWIST1 | twist family bHLH transcription factor 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| VAV3 | vav 3 guanine nucleotide exchange factor |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon |
| ZBED1 | zinc finger, BED-type containing 1 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZWINT | ZW10 interacting kinetochore protein |
