| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
| Downloads & Tools |
93 genes differentially expressed following the BRD-K86797399_pracinostat_HEPG2_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADAM10 | ADAM metallopeptidase domain 10 |
| ADGRE5 | adhesion G protein-coupled receptor E5 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ASPN | asporin |
| CD9 | CD9 molecule |
| CDC42 | cell division cycle 42 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| CTGF | connective tissue growth factor |
| CTSB | cathepsin B |
| CTSZ | cathepsin Z |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DUSP6 | dual specificity phosphatase 6 |
| FNDC3B | fibronectin type III domain containing 3B |
| GOLM1 | golgi membrane protein 1 |
| GREM1 | gremlin 1, DAN family BMP antagonist |
| ICAM1 | intercellular adhesion molecule 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IRS1 | insulin receptor substrate 1 |
| ISOC1 | isochorismatase domain containing 1 |
| JUNB | jun B proto-oncogene |
| LRP10 | low density lipoprotein receptor-related protein 10 |
| LUM | lumican |
| MAPT | microtubule-associated protein tau |
| MEIS1 | Meis homeobox 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MPPED2 | metallophosphoesterase domain containing 2 |
| NCAM1 | neural cell adhesion molecule 1 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PDGFC | platelet derived growth factor C |
| PFKM | phosphofructokinase, muscle |
| PLLP | plasmolipin |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTN | pleiotrophin |
| RBP1 | retinol binding protein 1, cellular |
| S100A4 | S100 calcium binding protein A4 |
| SCPEP1 | serine carboxypeptidase 1 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa |
| SULF1 | sulfatase 1 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 |
| TPM2 | tropomyosin 2 (beta) |
| TPP1 | tripeptidyl peptidase I |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VNN1 | vanin 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| WT1 | Wilms tumor 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| ACAT1 | acetyl-CoA acetyltransferase 1 |
| AKT1 | v-akt murine thymoma viral oncogene homolog 1 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATMIN | ATM interactor |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| CCNA2 | cyclin A2 |
| CD99 | CD99 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CLEC3B | C-type lectin domain family 3, member B |
| CNR1 | cannabinoid receptor 1 (brain) |
| CSNK1A1 | casein kinase 1, alpha 1 |
| CTSH | cathepsin H |
| DBI | diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) |
| DCLK1 | doublecortin-like kinase 1 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DEFB1 | defensin, beta 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
| EPHX3 | epoxide hydrolase 3 |
| HBB | hemoglobin, beta |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HOPX | HOP homeobox |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| IRAK1 | interleukin-1 receptor-associated kinase 1 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 |
| KDM5D | lysine (K)-specific demethylase 5D |
| LMO3 | LIM domain only 3 (rhombotin-like 2) |
| NES | nestin |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| PPIF | peptidylprolyl isomerase F |
| SELENBP1 | selenium binding protein 1 |
| SFTPB | surfactant protein B |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SPRR1A | small proline-rich protein 1A |
| SQLE | squalene epoxidase |
| TCF4 | transcription factor 4 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| WHSC1 | Wolf-Hirschhorn syndrome candidate 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
