Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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115 genes differentially expressed following the BRD-K86930074_S1017_MCF7_24.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
AMIGO2 | adhesion molecule with Ig-like domain 2 |
AQP1 | aquaporin 1 (Colton blood group) |
ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
BLNK | B-cell linker |
BTG2 | BTG family, member 2 |
CCND2 | cyclin D2 |
CD24 | CD24 molecule |
CD9 | CD9 molecule |
CDH13 | cadherin 13 |
CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
CKAP4 | cytoskeleton-associated protein 4 |
CLCA4 | chloride channel accessory 4 |
CPA3 | carboxypeptidase A3 (mast cell) |
CPE | carboxypeptidase E |
CRISP3 | cysteine-rich secretory protein 3 |
DHDDS | dehydrodolichyl diphosphate synthase |
DPYSL3 | dihydropyrimidinase-like 3 |
ECM1 | extracellular matrix protein 1 |
EFNA1 | ephrin-A1 |
FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
FILIP1L | filamin A interacting protein 1-like |
FN1 | fibronectin 1 |
FRY | furry homolog (Drosophila) |
GREM1 | gremlin 1, DAN family BMP antagonist |
HIST2H2BE | histone cluster 2, H2be |
INSM1 | insulinoma-associated 1 |
IPO13 | importin 13 |
KRT18 | keratin 18, type I |
LAPTM5 | lysosomal protein transmembrane 5 |
MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 |
MVP | major vault protein |
MYO1D | myosin ID |
NSDHL | NAD(P) dependent steroid dehydrogenase-like |
NXN | nucleoredoxin |
OBSL1 | obscurin-like 1 |
OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin |
PAWR | PRKC, apoptosis, WT1, regulator |
PELI1 | pellino E3 ubiquitin protein ligase 1 |
PTPRE | protein tyrosine phosphatase, receptor type, E |
RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
RBPMS | RNA binding protein with multiple splicing |
RGCC | regulator of cell cycle |
S100A8 | S100 calcium binding protein A8 |
S100A9 | S100 calcium binding protein A9 |
SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 |
SNX7 | sorting nexin 7 |
SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
ST18 | suppression of tumorigenicity 18, zinc finger |
STON1 | stonin 1 |
SULF1 | sulfatase 1 |
TPSAB1 | tryptase alpha/beta 1 |
VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
VAMP8 | vesicle-associated membrane protein 8 |
VWF | von Willebrand factor |
WIPI1 | WD repeat domain, phosphoinositide interacting 1 |
XIST | X inactive specific transcript (non-protein coding) |
YPEL5 | yippee-like 5 (Drosophila) |
Symbol | Name |
---|---|
AMD1 | adenosylmethionine decarboxylase 1 |
ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
ATF1 | activating transcription factor 1 |
CDC20 | cell division cycle 20 |
CDC42 | cell division cycle 42 |
CDK6 | cyclin-dependent kinase 6 |
CLINT1 | clathrin interactor 1 |
CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
CTSH | cathepsin H |
CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
EIF1AY | eukaryotic translation initiation factor 1A, Y-linked |
EIF4E | eukaryotic translation initiation factor 4E |
FABP5 | fatty acid binding protein 5 (psoriasis-associated) |
FOLR1 | folate receptor 1 (adult) |
G3BP1 | GTPase activating protein (SH3 domain) binding protein 1 |
GCH1 | GTP cyclohydrolase 1 |
HMGA1 | high mobility group AT-hook 1 |
HNRNPL | heterogeneous nuclear ribonucleoprotein L |
IFI6 | interferon, alpha-inducible protein 6 |
IFRD2 | interferon-related developmental regulator 2 |
KDM5D | lysine (K)-specific demethylase 5D |
KRT10 | keratin 10, type I |
KYNU | kynureninase |
LSM6 | LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
MARCKS | myristoylated alanine-rich protein kinase C substrate |
NBN | nibrin |
NCK1 | NCK adaptor protein 1 |
NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
NOLC1 | nucleolar and coiled-body phosphoprotein 1 |
NPY | neuropeptide Y |
NUTF2 | nuclear transport factor 2 |
PAK1IP1 | PAK1 interacting protein 1 |
PMP22 | peripheral myelin protein 22 |
PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
PTDSS1 | phosphatidylserine synthase 1 |
PTP4A2 | protein tyrosine phosphatase type IVA, member 2 |
RCN2 | reticulocalbin 2, EF-hand calcium binding domain |
RGS4 | regulator of G-protein signaling 4 |
RPP25 | ribonuclease P/MRP 25kDa subunit |
RYK | receptor-like tyrosine kinase |
SCML1 | sex comb on midleg-like 1 (Drosophila) |
SET | SET nuclear proto-oncogene |
SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 |
SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
SLIRP | SRA stem-loop interacting RNA binding protein |
SMAD3 | SMAD family member 3 |
SRSF1 | serine/arginine-rich splicing factor 1 |
TMPO | thymopoietin |
TOP2A | topoisomerase (DNA) II alpha 170kDa |
TSPYL5 | TSPY-like 5 |
UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
UBR7 | ubiquitin protein ligase E3 component n-recognin 7 (putative) |
WDR12 | WD repeat domain 12 |
WWTR1 | WW domain containing transcription regulator 1 |