BRD-K87737963_CYT387_BT20_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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42 genes differentially expressed following the BRD-K87737963_CYT387_BT20_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
DUSP4 dual specificity phosphatase 4
EREG epiregulin
FOSL1 FOS-like antigen 1
HDGFRP3 hepatoma-derived growth factor, related protein 3
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
NRP1 neuropilin 1
PLAUR plasminogen activator, urokinase receptor
S100A2 S100 calcium binding protein A2
SIK1 salt-inducible kinase 1
TSPAN1 tetraspanin 1

decreased expression

Symbol Name
ADD3 adducin 3 (gamma)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
BEX1 brain expressed, X-linked 1
CD99 CD99 molecule
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CSRP2 cysteine and glycine-rich protein 2
DCN decorin
DLK1 delta-like 1 homolog (Drosophila)
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DPYSL3 dihydropyrimidinase-like 3
EMP2 epithelial membrane protein 2
FAM129A family with sequence similarity 129, member A
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GCH1 GTP cyclohydrolase 1
GPM6B glycoprotein M6B
HOPX HOP homeobox
INSIG1 insulin induced gene 1
NPTX1 neuronal pentraxin I
NRIP1 nuclear receptor interacting protein 1
NRN1 neuritin 1
PCP4 Purkinje cell protein 4
PLK1 polo-like kinase 1
PTGIS prostaglandin I2 (prostacyclin) synthase
SCGB1D2 secretoglobin, family 1D, member 2
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SORBS1 sorbin and SH3 domain containing 1
THBS2 thrombospondin 2
THBS4 thrombospondin 4
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TMEM176B transmembrane protein 176B
TUBB2B tubulin, beta 2B class IIb