BRD-K87737963_CYT387_HS578T_3_h_3.33_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

87 genes differentially expressed following the BRD-K87737963_CYT387_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACP6 acid phosphatase 6, lysophosphatidic
ARF3 ADP-ribosylation factor 3
ARPP19 cAMP-regulated phosphoprotein, 19kDa
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
DDIT4 DNA-damage-inducible transcript 4
DSG2 desmoglein 2
EFNB2 ephrin-B2
EPN2 epsin 2
HOPX HOP homeobox
IFI6 interferon, alpha-inducible protein 6
LPAR2 lysophosphatidic acid receptor 2
LYN LYN proto-oncogene, Src family tyrosine kinase
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic
MSMB microseminoprotein, beta-
NRGN neurogranin (protein kinase C substrate, RC3)
NRP1 neuropilin 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PGC progastricsin (pepsinogen C)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
PLTP phospholipid transfer protein
PRKCB protein kinase C, beta
RNASE1 ribonuclease, RNase A family, 1 (pancreatic)
SEL1L3 sel-1 suppressor of lin-12-like 3 (C. elegans)
SFTPA2 surfactant protein A2
SFTPB surfactant protein B
STX1A syntaxin 1A (brain)
TSC22D1 TSC22 domain family, member 1

decreased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ABLIM1 actin binding LIM protein 1
ADM adrenomedullin
AEBP1 AE binding protein 1
ARID5B AT rich interactive domain 5B (MRF1-like)
BAMBI BMP and activin membrane-bound inhibitor
BGN biglycan
C10ORF10 chromosome 10 open reading frame 10
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1
CCL2 chemokine (C-C motif) ligand 2
CD24 CD24 molecule
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CELF2 CUGBP, Elav-like family member 2
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CLIC3 chloride intracellular channel 3
CLTB clathrin, light chain B
COL10A1 collagen, type X, alpha 1
COL11A1 collagen, type XI, alpha 1
COMP cartilage oligomeric matrix protein
CTGF connective tissue growth factor
CYR61 cysteine-rich, angiogenic inducer, 61
DCN decorin
DSP desmoplakin
DUSP5 dual specificity phosphatase 5
EDN1 endothelin 1
EFHD1 EF-hand domain family, member D1
EIF5A eukaryotic translation initiation factor 5A
FILIP1L filamin A interacting protein 1-like
FZD7 frizzled class receptor 7
GADD45A growth arrest and DNA-damage-inducible, alpha
GADD45B growth arrest and DNA-damage-inducible, beta
GCH1 GTP cyclohydrolase 1
HOXC6 homeobox C6
HSPA2 heat shock 70kDa protein 2
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
IGL immunoglobulin lambda locus
IL32 interleukin 32
INHBA inhibin, beta A
IRS2 insulin receptor substrate 2
JCHAIN joining chain of multimeric IgA and IgM
KIAA0355 KIAA0355
LUM lumican
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAN1A1 mannosidase, alpha, class 1A, member 1
MFAP5 microfibrillar associated protein 5
PELI1 pellino E3 ubiquitin protein ligase 1
PPL periplakin
PRKCH protein kinase C, eta
PTX3 pentraxin 3, long
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
SFRP4 secreted frizzled-related protein 4
SGK1 serum/glucocorticoid regulated kinase 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SULF1 sulfatase 1
THBS1 thrombospondin 1
THBS2 thrombospondin 2
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TRIM29 tripartite motif containing 29
VCAN versican
Funding