BRD-K87737963_CYT387_MDAMB231_3_h_1.11_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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75 genes differentially expressed following the BRD-K87737963_CYT387_MDAMB231_3_h_1.11_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ACSL3 acyl-CoA synthetase long-chain family member 3
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BHLHE40 basic helix-loop-helix family, member e40
CA2 carbonic anhydrase II
CD36 CD36 molecule (thrombospondin receptor)
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CLIC3 chloride intracellular channel 3
DDR1 discoidin domain receptor tyrosine kinase 1
DUSP4 dual specificity phosphatase 4
EREG epiregulin
FAM198B family with sequence similarity 198, member B
FAS Fas cell surface death receptor
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IL13RA2 interleukin 13 receptor, alpha 2
IL1B interleukin 1, beta
IL32 interleukin 32
KTN1 kinectin 1 (kinesin receptor)
LMAN1 lectin, mannose-binding, 1
LPL lipoprotein lipase
MALL mal, T-cell differentiation protein-like
OBSL1 obscurin-like 1
PGC progastricsin (pepsinogen C)
PPP1R13B protein phosphatase 1, regulatory subunit 13B
S100P S100 calcium binding protein P
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1
STX1A syntaxin 1A (brain)
USP6NL USP6 N-terminal like

decreased expression

Symbol Name
ACPP acid phosphatase, prostate
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1
ADD3 adducin 3 (gamma)
CALB1 calbindin 1, 28kDa
CAPN1 calpain 1, (mu/I) large subunit
CDC25A cell division cycle 25A
COL1A1 collagen, type I, alpha 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL8 chemokine (C-X-C motif) ligand 8
DPP4 dipeptidyl-peptidase 4
E2F2 E2F transcription factor 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
EPHA3 EPH receptor A3
F2R coagulation factor II (thrombin) receptor
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FST follistatin
GADD45B growth arrest and DNA-damage-inducible, beta
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3
GRIA2 glutamate receptor, ionotropic, AMPA 2
GUCY1B3 guanylate cyclase 1, soluble, beta 3
HOXC6 homeobox C6
HTATIP2 HIV-1 Tat interactive protein 2, 30kDa
IGFBP4 insulin-like growth factor binding protein 4
LCN2 lipocalin 2
MAP1B microtubule-associated protein 1B
MAPT microtubule-associated protein tau
MID1 midline 1
MUC1 mucin 1, cell surface associated
NEFH neurofilament, heavy polypeptide
OLFM4 olfactomedin 4
PFKP phosphofructokinase, platelet
RARRES1 retinoic acid receptor responder (tazarotene induced) 1
RHOBTB3 Rho-related BTB domain containing 3
SCN3A sodium channel, voltage gated, type III alpha subunit
SGK1 serum/glucocorticoid regulated kinase 1
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLCO1B3 solute carrier organic anion transporter family, member 1B3
SNAP25 synaptosomal-associated protein, 25kDa
SORD sorbitol dehydrogenase
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family)
TFPI2 tissue factor pathway inhibitor 2
WNT5A wingless-type MMTV integration site family, member 5A