BRD-K87904882_chelerythrine chloride_HCC515_24_h_0.04_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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60 genes differentially expressed following the BRD-K87904882_chelerythrine chloride_HCC515_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
AKR1C1 aldo-keto reductase family 1, member C1
AKR1C2 aldo-keto reductase family 1, member C2
ALCAM activated leukocyte cell adhesion molecule
APOD apolipoprotein D
ASCL1 achaete-scute family bHLH transcription factor 1
BASP1 brain abundant, membrane attached signal protein 1
CST6 cystatin E/M
CTGF connective tissue growth factor
DLK1 delta-like 1 homolog (Drosophila)
EPAS1 endothelial PAS domain protein 1
FABP4 fatty acid binding protein 4, adipocyte
KRT17 keratin 17, type I
KRT6A keratin 6A, type II
MSMB microseminoprotein, beta-
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
OBSL1 obscurin-like 1
PHACTR2 phosphatase and actin regulator 2
PROM1 prominin 1
PSPH phosphoserine phosphatase
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2
PXDN peroxidasin
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
S100P S100 calcium binding protein P
SOCS2 suppressor of cytokine signaling 2
SPTSSA serine palmitoyltransferase, small subunit A
TFF3 trefoil factor 3 (intestinal)
TMC5 transmembrane channel-like 5
VDAC1 voltage-dependent anion channel 1

decreased expression

Symbol Name
AURKB aurora kinase B
BPHL biphenyl hydrolase-like (serine hydrolase)
C6ORF62 chromosome 6 open reading frame 62
CDC42SE1 CDC42 small effector 1
CFD complement factor D (adipsin)
CTTN cortactin
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
DNM1L dynamin 1-like
EIF4B eukaryotic translation initiation factor 4B
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
HOXB6 homeobox B6
IGHD immunoglobulin heavy constant delta
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGLJ3 immunoglobulin lambda joining 3
IL13RA2 interleukin 13 receptor, alpha 2
IL32 interleukin 32
LIMCH1 LIM and calponin homology domains 1
LTBP3 latent transforming growth factor beta binding protein 3
PON3 paraoxonase 3
PRKACB protein kinase, cAMP-dependent, catalytic, beta
REXO2 RNA exonuclease 2
RHOBTB3 Rho-related BTB domain containing 3
RPL27A ribosomal protein L27a
RPL38 ribosomal protein L38
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TPD52 tumor protein D52
TSC22D1 TSC22 domain family, member 1
TUBB2B tubulin, beta 2B class IIb
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)