| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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223 genes differentially expressed following the BRD-K87909389_alvocidib_BT20_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ADRB2 | adrenoceptor beta 2, surface |
| AIF1 | allograft inflammatory factor 1 |
| ANKRD36B | ankyrin repeat domain 36B |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) |
| ASPN | asporin |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BLNK | B-cell linker |
| BSG | basigin (Ok blood group) |
| CALD1 | caldesmon 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CERS6 | ceramide synthase 6 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL5A2 | collagen, type V, alpha 2 |
| COL6A3 | collagen, type VI, alpha 3 |
| CPE | carboxypeptidase E |
| CTBS | chitobiase, di-N-acetyl- |
| CTGF | connective tissue growth factor |
| CTSC | cathepsin C |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 |
| DYNLT3 | dynein, light chain, Tctex-type 3 |
| ECHDC2 | enoyl CoA hydratase domain containing 2 |
| ECM1 | extracellular matrix protein 1 |
| EGR1 | early growth response 1 |
| ENO1 | enolase 1, (alpha) |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ESR1 | estrogen receptor 1 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM162A | family with sequence similarity 162, member A |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 |
| FOLR1 | folate receptor 1 (adult) |
| GAS6 | growth arrest-specific 6 |
| GNB5 | guanine nucleotide binding protein (G protein), beta 5 |
| GNL3L | guanine nucleotide binding protein-like 3 (nucleolar)-like |
| GOLGA8A | golgin A8 family, member A |
| GOLGA8B | golgin A8 family, member B |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX3 | glutathione peroxidase 3 |
| GSAP | gamma-secretase activating protein |
| GUK1 | guanylate kinase 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HIST1H1C | histone cluster 1, H1c |
| IDS | iduronate 2-sulfatase |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| ITGAV | integrin, alpha V |
| ITM2A | integral membrane protein 2A |
| KCTD12 | potassium channel tetramerization domain containing 12 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase |
| MBP | myelin basic protein |
| MEIS1 | Meis homeobox 1 |
| MXRA5 | matrix-remodelling associated 5 |
| MXRA7 | matrix-remodelling associated 7 |
| MYLK | myosin light chain kinase |
| MYO6 | myosin VI |
| NME1 | NME/NM23 nucleoside diphosphate kinase 1 |
| NREP | neuronal regeneration related protein |
| OSBPL1A | oxysterol binding protein-like 1A |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase |
| PEG3 | paternally expressed 3 |
| PLVAP | plasmalemma vesicle associated protein |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa |
| PPBP | pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) |
| PRDX4 | peroxiredoxin 4 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PSPH | phosphoserine phosphatase |
| PTN | pleiotrophin |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP4 | retinol binding protein 4, plasma |
| REEP5 | receptor accessory protein 5 |
| SAMSN1 | SAM domain, SH3 domain and nuclear localization signals 1 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) |
| SCG5 | secretogranin V |
| SCP2 | sterol carrier protein 2 |
| SDC2 | syndecan 2 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like |
| SLC16A7 | solute carrier family 16 (monocarboxylate transporter), member 7 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 |
| SMYD3 | SET and MYND domain containing 3 |
| SOCS2 | suppressor of cytokine signaling 2 |
| SRPR | signal recognition particle receptor (docking protein) |
| SSR1 | signal sequence receptor, alpha |
| SSR3 | signal sequence receptor, gamma (translocon-associated protein gamma) |
| SSR4 | signal sequence receptor, delta |
| STC1 | stanniocalcin 1 |
| TBC1D9B | TBC1 domain family, member 9B (with GRAM domain) |
| THBS1 | thrombospondin 1 |
| THY1 | Thy-1 cell surface antigen |
| TIMP3 | TIMP metallopeptidase inhibitor 3 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMEM14B | transmembrane protein 14B |
| TMEM259 | transmembrane protein 259 |
| TMEM45A | transmembrane protein 45A |
| TPP1 | tripeptidyl peptidase I |
| TRA2A | transformer 2 alpha homolog (Drosophila) |
| TSPAN7 | tetraspanin 7 |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| VEGFA | vascular endothelial growth factor A |
| Symbol | Name |
|---|---|
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) |
| ANXA3 | annexin A3 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARID4B | AT rich interactive domain 4B (RBP1-like) |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATMIN | ATM interactor |
| AURKA | aurora kinase A |
| BLCAP | bladder cancer associated protein |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CAB39 | calcium binding protein 39 |
| CBR3 | carbonyl reductase 3 |
| CCNA2 | cyclin A2 |
| CCNB1 | cyclin B1 |
| CCNB2 | cyclin B2 |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDCA3 | cell division cycle associated 3 |
| CDCA8 | cell division cycle associated 8 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 |
| CENPA | centromere protein A |
| CENPE | centromere protein E, 312kDa |
| CENPF | centromere protein F, 350/400kDa |
| CENPN | centromere protein N |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CLTA | clathrin, light chain A |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CSNK1D | casein kinase 1, delta |
| CSTF1 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DAPK1 | death-associated protein kinase 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FHL2 | four and a half LIM domains 2 |
| FOXO3 | forkhead box O3 |
| FZD7 | frizzled class receptor 7 |
| GATA3 | GATA binding protein 3 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A |
| GPSM2 | G-protein signaling modulator 2 |
| GPX2 | glutathione peroxidase 2 |
| H2AFX | H2A histone family, member X |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA8 | heat shock 70kDa protein 8 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IRS2 | insulin receptor substrate 2 |
| KAZN | kazrin, periplakin interacting protein |
| KIF20A | kinesin family member 20A |
| KIF23 | kinesin family member 23 |
| KRT17 | keratin 17, type I |
| KRT18 | keratin 18, type I |
| KRT7 | keratin 7, type II |
| LBR | lamin B receptor |
| LXN | latexin |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MBNL2 | muscleblind-like splicing regulator 2 |
| MELK | maternal embryonic leucine zipper kinase |
| MGP | matrix Gla protein |
| MICALL1 | MICAL-like 1 |
| MKI67 | marker of proliferation Ki-67 |
| MMP7 | matrix metallopeptidase 7 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDC80 | NDC80 kinetochore complex component |
| NEK2 | NIMA-related kinase 2 |
| NNMT | nicotinamide N-methyltransferase |
| NPY1R | neuropeptide Y receptor Y1 |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OLFM4 | olfactomedin 4 |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PLK1 | polo-like kinase 1 |
| PRC1 | protein regulator of cytokinesis 1 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| PUF60 | poly-U binding splicing factor 60KDa |
| PUM1 | pumilio RNA-binding family member 1 |
| RAE1 | ribonucleic acid export 1 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RNF114 | ring finger protein 114 |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| S100A7 | S100 calcium binding protein A7 |
| S100P | S100 calcium binding protein P |
| SCAND1 | SCAN domain containing 1 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SFN | stratifin |
| SLC38A2 | solute carrier family 38, member 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SRGN | serglycin |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| SYNRG | synergin, gamma |
| TAB2 | TGF-beta activated kinase 1/MAP3K7 binding protein 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TFAP2C | transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TJP2 | tight junction protein 2 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TPX2 | TPX2, microtubule-associated |
| TSPYL5 | TSPY-like 5 |
| TTK | TTK protein kinase |
| TUBB4B | tubulin, beta 4B class IVb |
| TXLNA | taxilin alpha |
| U2AF1 | U2 small nuclear RNA auxiliary factor 1 |
| UBE2C | ubiquitin-conjugating enzyme E2C |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP1 | ubiquitin specific peptidase 1 |
| USP22 | ubiquitin specific peptidase 22 |
| VAPB | VAMP (vesicle-associated membrane protein)-associated protein B and C |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) |
| WDR82 | WD repeat domain 82 |
| WEE1 | WEE1 G2 checkpoint kinase |
| YKT6 | YKT6 v-SNARE homolog (S. cerevisiae) |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |
| ZNF217 | zinc finger protein 217 |
