| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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209 genes differentially expressed following the BRD-K87909389_alvocidib_HME1_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCB1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTC1 | actin, alpha, cardiac muscle 1 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| AIF1 | allograft inflammatory factor 1 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| C10ORF2 | chromosome 10 open reading frame 2 |
| C8ORF33 | chromosome 8 open reading frame 33 |
| CALB1 | calbindin 1, 28kDa |
| CALD1 | caldesmon 1 |
| CCDC6 | coiled-coil domain containing 6 |
| CCDC93 | coiled-coil domain containing 93 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD163 | CD163 molecule |
| CFD | complement factor D (adipsin) |
| CHERP | calcium homeostasis endoplasmic reticulum protein |
| CIAPIN1 | cytokine induced apoptosis inhibitor 1 |
| CLDN3 | claudin 3 |
| CPE | carboxypeptidase E |
| CRABP1 | cellular retinoic acid binding protein 1 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CRYAB | crystallin, alpha B |
| CTSZ | cathepsin Z |
| CYB5A | cytochrome b5 type A (microsomal) |
| DACH1 | dachshund family transcription factor 1 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 |
| DNTTIP2 | deoxynucleotidyltransferase, terminal, interacting protein 2 |
| DSC2 | desmocollin 2 |
| EFNA1 | ephrin-A1 |
| ESR1 | estrogen receptor 1 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 |
| F12 | coagulation factor XII (Hageman factor) |
| FAM63A | family with sequence similarity 63, member A |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FOLR1 | folate receptor 1 (adult) |
| FOXJ3 | forkhead box J3 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA6 | GATA binding protein 6 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLS | glutaminase |
| GMFB | glia maturation factor, beta |
| GRN | granulin |
| GSTM3 | glutathione S-transferase mu 3 (brain) |
| HMOX1 | heme oxygenase 1 |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPB8 | heat shock 22kDa protein 8 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| JAG1 | jagged 1 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP2K3 | mitogen-activated protein kinase kinase 3 |
| NDRG1 | N-myc downstream regulated 1 |
| PALLD | palladin, cytoskeletal associated protein |
| PCP4 | Purkinje cell protein 4 |
| PEG10 | paternally expressed 10 |
| PEG3 | paternally expressed 3 |
| PHF20 | PHD finger protein 20 |
| PIK3IP1 | phosphoinositide-3-kinase interacting protein 1 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| PLIN2 | perilipin 2 |
| PPARD | peroxisome proliferator-activated receptor delta |
| PRR7 | proline rich 7 (synaptic) |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) |
| RABGGTB | Rab geranylgeranyltransferase, beta subunit |
| RAE1 | ribonucleic acid export 1 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) |
| RAP1GAP2 | RAP1 GTPase activating protein 2 |
| RARA | retinoic acid receptor, alpha |
| RBP1 | retinol binding protein 1, cellular |
| RIOK3 | RIO kinase 3 |
| RNMT | RNA (guanine-7-) methyltransferase |
| RPL28 | ribosomal protein L28 |
| RPL31 | ribosomal protein L31 |
| RSL1D1 | ribosomal L1 domain containing 1 |
| S100A8 | S100 calcium binding protein A8 |
| SATB2 | SATB homeobox 2 |
| SCG5 | secretogranin V |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SFRP4 | secreted frizzled-related protein 4 |
| SGSH | N-sulfoglucosamine sulfohydrolase |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD7 | SMAD family member 7 |
| SNN | stannin |
| SPEN | spen family transcriptional repressor |
| SRSF11 | serine/arginine-rich splicing factor 11 |
| SST | somatostatin |
| STMN2 | stathmin 2 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa |
| TAGLN | transgelin |
| TICAM1 | toll-like receptor adaptor molecule 1 |
| TMEM176B | transmembrane protein 176B |
| TMEM45A | transmembrane protein 45A |
| TPD52L1 | tumor protein D52-like 1 |
| TPP1 | tripeptidyl peptidase I |
| TSPAN12 | tetraspanin 12 |
| TSPAN7 | tetraspanin 7 |
| UTP14A | UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast) |
| WT1 | Wilms tumor 1 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| Symbol | Name |
|---|---|
| ACSL3 | acyl-CoA synthetase long-chain family member 3 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) |
| ATF5 | activating transcription factor 5 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked |
| AURKA | aurora kinase A |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding |
| BLMH | bleomycin hydrolase |
| C4ORF27 | chromosome 4 open reading frame 27 |
| CAST | calpastatin |
| CBR3 | carbonyl reductase 3 |
| CBX1 | chromobox homolog 1 |
| CDCA3 | cell division cycle associated 3 |
| CENPE | centromere protein E, 312kDa |
| CEP55 | centrosomal protein 55kDa |
| CHD9 | chromodomain helicase DNA binding protein 9 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| COL4A5 | collagen, type IV, alpha 5 |
| COL5A2 | collagen, type V, alpha 2 |
| DENND1B | DENN/MADD domain containing 1B |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DMD | dystrophin |
| DPYSL2 | dihydropyrimidinase-like 2 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EIF5A | eukaryotic translation initiation factor 5A |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ETV5 | ets variant 5 |
| FADS1 | fatty acid desaturase 1 |
| FAM129A | family with sequence similarity 129, member A |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 |
| FKBP11 | FK506 binding protein 11, 19 kDa |
| FZD7 | frizzled class receptor 7 |
| GALE | UDP-galactose-4-epimerase |
| GAS1 | growth arrest-specific 1 |
| GTPBP8 | GTP-binding protein 8 (putative) |
| GTSE1 | G-2 and S-phase expressed 1 |
| HOXB2 | homeobox B2 |
| HOXB7 | homeobox B7 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IFI16 | interferon, gamma-inducible protein 16 |
| IGHM | immunoglobulin heavy constant mu |
| IGLV2-23 | immunoglobulin lambda variable 2-23 |
| ITGB4 | integrin, beta 4 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) |
| JADE2 | jade family PHD finger 2 |
| JCHAIN | joining chain of multimeric IgA and IgM |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIF14 | kinesin family member 14 |
| KIF20A | kinesin family member 20A |
| LOXL2 | lysyl oxidase-like 2 |
| LXN | latexin |
| MACF1 | microtubule-actin crosslinking factor 1 |
| MAGED1 | melanoma antigen family D1 |
| MANSC1 | MANSC domain containing 1 |
| MET | MET proto-oncogene, receptor tyrosine kinase |
| MKI67 | marker of proliferation Ki-67 |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MSMB | microseminoprotein, beta- |
| MYH10 | myosin, heavy chain 10, non-muscle |
| NMI | N-myc (and STAT) interactor |
| NNMT | nicotinamide N-methyltransferase |
| NT5E | 5'-nucleotidase, ecto (CD73) |
| NTS | neurotensin |
| NUSAP1 | nucleolar and spindle associated protein 1 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa |
| OSBPL8 | oxysterol binding protein-like 8 |
| PAIP1 | poly(A) binding protein interacting protein 1 |
| PCM1 | pericentriolar material 1 |
| PLK1 | polo-like kinase 1 |
| PLS1 | plastin 1 |
| PLSCR1 | phospholipid scramblase 1 |
| POU2AF1 | POU class 2 associating factor 1 |
| PRKD3 | protein kinase D3 |
| PSMC2 | proteasome (prosome, macropain) 26S subunit, ATPase, 2 |
| PURA | purine-rich element binding protein A |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RDX | radixin |
| RGS2 | regulator of G-protein signaling 2 |
| RRM2 | ribonucleotide reductase M2 |
| SFRP1 | secreted frizzled-related protein 1 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 |
| SMC4 | structural maintenance of chromosomes 4 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| STMN1 | stathmin 1 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
| TCF4 | transcription factor 4 |
| TESC | tescalcin |
| THBS2 | thrombospondin 2 |
| TIA1 | TIA1 cytotoxic granule-associated RNA binding protein |
| TMSB15A | thymosin beta 15a |
| TOP2A | topoisomerase (DNA) II alpha 170kDa |
| TRIM29 | tripartite motif containing 29 |
| TUBB | tubulin, beta class I |
| TUBB4B | tubulin, beta 4B class IVb |
| TXNIP | thioredoxin interacting protein |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| VCAN | versican |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| ZBTB38 | zinc finger and BTB domain containing 38 |
