| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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216 genes differentially expressed following the BRD-K87909389_alvocidib_MCF10A_24_h_0.04_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AHNAK | AHNAK nucleoprotein |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AIF1 | allograft inflammatory factor 1 |
| AKR1C1 | aldo-keto reductase family 1, member C1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ANXA4 | annexin A4 |
| AQP1 | aquaporin 1 (Colton blood group) |
| BASP1 | brain abundant, membrane attached signal protein 1 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| C10ORF10 | chromosome 10 open reading frame 10 |
| C1R | complement component 1, r subcomponent |
| CALB1 | calbindin 1, 28kDa |
| CD300A | CD300a molecule |
| CD53 | CD53 molecule |
| CELF2 | CUGBP, Elav-like family member 2 |
| CFD | complement factor D (adipsin) |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CLCA2 | chloride channel accessory 2 |
| CLEC3B | C-type lectin domain family 3, member B |
| COLEC12 | collectin sub-family member 12 |
| CRABP2 | cellular retinoic acid binding protein 2 |
| CSTA | cystatin A (stefin A) |
| CYBB | cytochrome b-245, beta polypeptide |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FABP4 | fatty acid binding protein 4, adipocyte |
| FAM127A | family with sequence similarity 127, member A |
| FBLN1 | fibulin 1 |
| FCGR2B | Fc fragment of IgG, low affinity IIb, receptor (CD32) |
| FEZ1 | fasciculation and elongation protein zeta 1 (zygin I) |
| FHL1 | four and a half LIM domains 1 |
| FOLR1 | folate receptor 1 (adult) |
| GPM6B | glycoprotein M6B |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 |
| H2BFS | H2B histone family, member S (pseudogene) |
| HBB | hemoglobin, beta |
| HIST1H1C | histone cluster 1, H1c |
| HIST1H2AC | histone cluster 1, H2ac |
| HIST1H2BD | histone cluster 1, H2bd |
| HIST1H2BK | histone cluster 1, H2bk |
| HIST1H3H | histone cluster 1, H3h |
| HMOX1 | heme oxygenase 1 |
| IFNGR1 | interferon gamma receptor 1 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JAG1 | jagged 1 |
| KRT6A | keratin 6A, type II |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LST1 | leukocyte specific transcript 1 |
| MAN2B1 | mannosidase, alpha, class 2B, member 1 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MFAP5 | microfibrillar associated protein 5 |
| MMD | monocyte to macrophage differentiation-associated |
| MMP7 | matrix metallopeptidase 7 |
| MYH11 | myosin, heavy chain 11, smooth muscle |
| NCF2 | neutrophil cytosolic factor 2 |
| NDRG1 | N-myc downstream regulated 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| OSR2 | odd-skipped related transciption factor 2 |
| OXSR1 | oxidative stress responsive 1 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) |
| PDGFD | platelet derived growth factor D |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDZK1IP1 | PDZK1 interacting protein 1 |
| PEG10 | paternally expressed 10 |
| PHF20 | PHD finger protein 20 |
| PI3 | peptidase inhibitor 3, skin-derived |
| PLXNB2 | plexin B2 |
| PPAP2B | phosphatidic acid phosphatase type 2B |
| PPL | periplakin |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPRC | protein tyrosine phosphatase, receptor type, C |
| PYCARD | PYD and CARD domain containing |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) |
| RPL31 | ribosomal protein L31 |
| S100A7 | S100 calcium binding protein A7 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
| SGCE | sarcoglycan, epsilon |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 |
| ST6GAL1 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) |
| TMEM45A | transmembrane protein 45A |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TNIP1 | TNFAIP3 interacting protein 1 |
| TNS3 | tensin 3 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TPP1 | tripeptidyl peptidase I |
| TSC22D3 | TSC22 domain family, member 3 |
| TSKU | tsukushi, small leucine rich proteoglycan |
| TUBB2B | tubulin, beta 2B class IIb |
| TXNIP | thioredoxin interacting protein |
| WISP2 | WNT1 inducible signaling pathway protein 2 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZIC1 | Zic family member 1 |
| Symbol | Name |
|---|---|
| ADI1 | acireductone dioxygenase 1 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| ANP32E | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E |
| ANXA2 | annexin A2 |
| ANXA3 | annexin A3 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ATF5 | activating transcription factor 5 |
| AURKB | aurora kinase B |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger |
| CACYBP | calcyclin binding protein |
| CCK | cholecystokinin |
| CCNA2 | cyclin A2 |
| CCNF | cyclin F |
| CD81 | CD81 molecule |
| CDC25A | cell division cycle 25A |
| CDC6 | cell division cycle 6 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) |
| CENPN | centromere protein N |
| CENPU | centromere protein U |
| CEP55 | centrosomal protein 55kDa |
| CHMP4A | charged multivesicular body protein 4A |
| CKS2 | CDC28 protein kinase regulatory subunit 2 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) |
| CXCL9 | chemokine (C-X-C motif) ligand 9 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DBF4 | DBF4 zinc finger |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJC9 | DnaJ (Hsp40) homolog, subfamily C, member 9 |
| DONSON | downstream neighbor of SON |
| DTL | denticleless E3 ubiquitin protein ligase homolog (Drosophila) |
| DUSP2 | dual specificity phosphatase 2 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked |
| ENOSF1 | enolase superfamily member 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit |
| FAM129A | family with sequence similarity 129, member A |
| FOSL1 | FOS-like antigen 1 |
| GAL | galanin/GMAP prepropeptide |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) |
| GNAS | GNAS complex locus |
| GTPBP8 | GTP-binding protein 8 (putative) |
| GTSE1 | G-2 and S-phase expressed 1 |
| GZMK | granzyme K (granzyme 3; tryptase II) |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 |
| HBEGF | heparin-binding EGF-like growth factor |
| HIST1H4C | histone cluster 1, H4c |
| HMGB1 | high mobility group box 1 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| JMJD6 | jumonji domain containing 6 |
| KIAA0101 | KIAA0101 |
| KIF14 | kinesin family member 14 |
| KIF20A | kinesin family member 20A |
| LBR | lamin B receptor |
| LIG1 | ligase I, DNA, ATP-dependent |
| MCM10 | minichromosome maintenance complex component 10 |
| MCM4 | minichromosome maintenance complex component 4 |
| MCM5 | minichromosome maintenance complex component 5 |
| MELK | maternal embryonic leucine zipper kinase |
| MMP9 | matrix metallopeptidase 9 |
| MYBL2 | v-myb avian myeloblastosis viral oncogene homolog-like 2 |
| NAP1L1 | nucleosome assembly protein 1-like 1 |
| NCAPG | non-SMC condensin I complex, subunit G |
| NPY | neuropeptide Y |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 |
| PHACTR2 | phosphatase and actin regulator 2 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PNN | pinin, desmosome associated protein |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit |
| PRDX2 | peroxiredoxin 2 |
| PRPS2 | phosphoribosyl pyrophosphate synthetase 2 |
| PSPH | phosphoserine phosphatase |
| RANBP1 | RAN binding protein 1 |
| RBPMS | RNA binding protein with multiple splicing |
| RRM1 | ribonucleotide reductase M1 |
| RRM2 | ribonucleotide reductase M2 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SEPT11 | septin 11 |
| SHCBP1 | SHC SH2-domain binding protein 1 |
| SKP1 | S-phase kinase-associated protein 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SMC4 | structural maintenance of chromosomes 4 |
| SNRPG | small nuclear ribonucleoprotein polypeptide G |
| SORD | sorbitol dehydrogenase |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) |
| SRSF3 | serine/arginine-rich splicing factor 3 |
| STMN1 | stathmin 1 |
| SUB1 | SUB1 homolog (S. cerevisiae) |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TDO2 | tryptophan 2,3-dioxygenase |
| TESC | tescalcin |
| TIPIN | TIMELESS interacting protein |
| TMEM47 | transmembrane protein 47 |
| TMPO | thymopoietin |
| TSPAN13 | tetraspanin 13 |
| TWF1 | twinfilin actin binding protein 1 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 |
| USP1 | ubiquitin specific peptidase 1 |
| WEE1 | WEE1 G2 checkpoint kinase |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta |
| ZWILCH | zwilch kinetochore protein |
