| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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185 genes differentially expressed following the BRD-K87909389_alvocidib_MDAMB231_24_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| A2M | alpha-2-macroglobulin |
| ABCG1 | ATP-binding cassette, sub-family G (WHITE), member 1 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 |
| AQP1 | aquaporin 1 (Colton blood group) |
| ASPN | asporin |
| ATF3 | activating transcription factor 3 |
| BACE2 | beta-site APP-cleaving enzyme 2 |
| BSG | basigin (Ok blood group) |
| C1QA | complement component 1, q subcomponent, A chain |
| C1QB | complement component 1, q subcomponent, B chain |
| C3 | complement component 3 |
| CADM1 | cell adhesion molecule 1 |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD320 | CD320 molecule |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CD48 | CD48 molecule |
| CETN2 | centrin, EF-hand protein, 2 |
| CFH | complement factor H |
| CKLF | chemokine-like factor |
| COL5A2 | collagen, type V, alpha 2 |
| CPE | carboxypeptidase E |
| CSF1R | colony stimulating factor 1 receptor |
| CSTA | cystatin A (stefin A) |
| CTTN | cortactin |
| CXADR | coxsackie virus and adenovirus receptor |
| CXCL13 | chemokine (C-X-C motif) ligand 13 |
| EGFL6 | EGF-like-domain, multiple 6 |
| EGR1 | early growth response 1 |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| FGFR3 | fibroblast growth factor receptor 3 |
| FHL1 | four and a half LIM domains 1 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) |
| FOXO4 | forkhead box O4 |
| GNAI1 | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 |
| GNAS | GNAS complex locus |
| GPNMB | glycoprotein (transmembrane) nmb |
| GPX3 | glutathione peroxidase 3 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| GUK1 | guanylate kinase 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HCAR3 | hydroxycarboxylic acid receptor 3 |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HGF | hepatocyte growth factor (hepapoietin A; scatter factor) |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein |
| IDS | iduronate 2-sulfatase |
| IFI27 | interferon, alpha-inducible protein 27 |
| IFI6 | interferon, alpha-inducible protein 6 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IL1R1 | interleukin 1 receptor, type I |
| ITGAV | integrin, alpha V |
| ITM2A | integral membrane protein 2A |
| ITM2C | integral membrane protein 2C |
| LAMP3 | lysosomal-associated membrane protein 3 |
| LUM | lumican |
| MAGEA3 | melanoma antigen family A3 |
| MAGEA6 | melanoma antigen family A6 |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MEIS1 | Meis homeobox 1 |
| MFAP5 | microfibrillar associated protein 5 |
| MMP9 | matrix metallopeptidase 9 |
| MT1M | metallothionein 1M |
| MXRA5 | matrix-remodelling associated 5 |
| MYL9 | myosin, light chain 9, regulatory |
| PALLD | palladin, cytoskeletal associated protein |
| PLAT | plasminogen activator, tissue |
| PLVAP | plasmalemma vesicle associated protein |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RBP1 | retinol binding protein 1, cellular |
| RBP4 | retinol binding protein 4, plasma |
| RGS5 | regulator of G-protein signaling 5 |
| RND3 | Rho family GTPase 3 |
| SCG2 | secretogranin II |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) |
| SDC2 | syndecan 2 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SLIT2 | slit homolog 2 (Drosophila) |
| SLPI | secretory leukocyte peptidase inhibitor |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPON1 | spondin 1, extracellular matrix protein |
| SPON2 | spondin 2, extracellular matrix protein |
| SSPN | sarcospan |
| TFPI2 | tissue factor pathway inhibitor 2 |
| THY1 | Thy-1 cell surface antigen |
| TNS1 | tensin 1 |
| TSPAN13 | tetraspanin 13 |
| TSPAN4 | tetraspanin 4 |
| TSPAN7 | tetraspanin 7 |
| TUSC3 | tumor suppressor candidate 3 |
| TYROBP | TYRO protein tyrosine kinase binding protein |
| VWF | von Willebrand factor |
| WNT5A | wingless-type MMTV integration site family, member 5A |
| XIST | X inactive specific transcript (non-protein coding) |
| Symbol | Name |
|---|---|
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B |
| ARF6 | ADP-ribosylation factor 6 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide |
| AURKA | aurora kinase A |
| BAG3 | BCL2-associated athanogene 3 |
| BTG1 | B-cell translocation gene 1, anti-proliferative |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase |
| CALML5 | calmodulin-like 5 |
| CCNA2 | cyclin A2 |
| CDC20 | cell division cycle 20 |
| CDC25B | cell division cycle 25B |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEP55 | centrosomal protein 55kDa |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DNMBP | dynamin binding protein |
| DUSP6 | dual specificity phosphatase 6 |
| FBL | fibrillarin |
| FOSL1 | FOS-like antigen 1 |
| FZD7 | frizzled class receptor 7 |
| HMGB2 | high mobility group box 2 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) |
| HSPA8 | heat shock 70kDa protein 8 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KEAP1 | kelch-like ECH-associated protein 1 |
| KIF20A | kinesin family member 20A |
| KLF4 | Kruppel-like factor 4 (gut) |
| LASP1 | LIM and SH3 protein 1 |
| LMNB1 | lamin B1 |
| LRIF1 | ligand dependent nuclear receptor interacting factor 1 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MARCKS | myristoylated alanine-rich protein kinase C substrate |
| MCM3 | minichromosome maintenance complex component 3 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MKI67 | marker of proliferation Ki-67 |
| MTCL1 | microtubule crosslinking factor 1 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| MYO10 | myosin X |
| NDC80 | NDC80 kinetochore complex component |
| NET1 | neuroepithelial cell transforming 1 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NOTCH2 | notch 2 |
| NUP62 | nucleoporin 62kDa |
| PCNA | proliferating cell nuclear antigen |
| PDE4B | phosphodiesterase 4B, cAMP-specific |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLK2 | polo-like kinase 2 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme |
| PRC1 | protein regulator of cytokinesis 1 |
| PSMG1 | proteasome (prosome, macropain) assembly chaperone 1 |
| PTX3 | pentraxin 3, long |
| RAD23B | RAD23 homolog B (S. cerevisiae) |
| RNPS1 | RNA binding protein S1, serine-rich domain |
| S100A7 | S100 calcium binding protein A7 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SMAD3 | SMAD family member 3 |
| SNRNP40 | small nuclear ribonucleoprotein 40kDa (U5) |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPP1 | secreted phosphoprotein 1 |
| TACC2 | transforming, acidic coiled-coil containing protein 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMPO | thymopoietin |
| TRAM2 | translocation associated membrane protein 2 |
| TRAPPC3 | trafficking protein particle complex 3 |
| TSPYL5 | TSPY-like 5 |
| TXLNA | taxilin alpha |
| UBE2S | ubiquitin-conjugating enzyme E2S |
| USP1 | ubiquitin specific peptidase 1 |
| USP22 | ubiquitin specific peptidase 22 |
| USP7 | ubiquitin specific peptidase 7 (herpes virus-associated) |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa |
| XPO7 | exportin 7 |
| YBX3 | Y box binding protein 3 |
