BRD-K88008216_-666_A375_6.0_h_10.0_um Gene Set

Dataset LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map)
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Genes

57 genes differentially expressed following the BRD-K88008216_-666_A375_6.0_h_10.0_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
1060P11.3 killer cell immunoglobulin-like receptor, three domains, pseudogene
ASNS asparagine synthetase (glutamine-hydrolyzing)
CCR2 chemokine (C-C motif) receptor 2
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
COL1A2 collagen, type I, alpha 2
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9
GUSBP11 glucuronidase, beta pseudogene 11
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HMOX1 heme oxygenase 1
HOXC6 homeobox C6
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IGHM immunoglobulin heavy constant mu
IGL immunoglobulin lambda locus
IGLJ3 immunoglobulin lambda joining 3
IGLV1-40 immunoglobulin lambda variable 1-40
IGLV2-23 immunoglobulin lambda variable 2-23
IGLV3-19 immunoglobulin lambda variable 3-19
IL13RA1 interleukin 13 receptor, alpha 1
MPO myeloperoxidase
PSD3 pleckstrin and Sec7 domain containing 3
RAI14 retinoic acid induced 14
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RTN1 reticulon 1
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SLC35F2 solute carrier family 35, member F2
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSC22D1 TSC22 domain family, member 1
VCAN versican
XBP1 X-box binding protein 1

decreased expression

Symbol Name
ADGRL2 adhesion G protein-coupled receptor L2
BASP1 brain abundant, membrane attached signal protein 1
C7 complement component 7
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CCND1 cyclin D1
CDH3 cadherin 3, type 1, P-cadherin (placental)
CELF2 CUGBP, Elav-like family member 2
DAPK1 death-associated protein kinase 1
EGFR epidermal growth factor receptor
FAM46A family with sequence similarity 46, member A
FXYD3 FXYD domain containing ion transport regulator 3
GBP1 guanylate binding protein 1, interferon-inducible
GPX2 glutathione peroxidase 2
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IKZF1 IKAROS family zinc finger 1 (Ikaros)
MARCKS myristoylated alanine-rich protein kinase C substrate
MEIS1 Meis homeobox 1
MEIS2 Meis homeobox 2
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1
PFN2 profilin 2
PLTP phospholipid transfer protein
RBP1 retinol binding protein 1, cellular
SPARCL1 SPARC-like 1 (hevin)
SRPX sushi-repeat containing protein, X-linked
TACSTD2 tumor-associated calcium signal transducer 2
TJP2 tight junction protein 2