| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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131 genes differentially expressed following the BRD-K88378636_withaferin-a_HME1_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ARHGEF2 | Rho/Rac guanine nucleotide exchange factor (GEF) 2 |
| ATF3 | activating transcription factor 3 |
| BAG3 | BCL2-associated athanogene 3 |
| BTG2 | BTG family, member 2 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CSRP2 | cysteine and glycine-rich protein 2 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| FAM46C | family with sequence similarity 46, member C |
| FBXL12 | F-box and leucine-rich repeat protein 12 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FXYD5 | FXYD domain containing ion transport regulator 5 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GAS1 | growth arrest-specific 1 |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 |
| HIST1H2BG | histone cluster 1, H2bg |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| HSPA8 | heat shock 70kDa protein 8 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 |
| IER2 | immediate early response 2 |
| IER5 | immediate early response 5 |
| IGFBP5 | insulin-like growth factor binding protein 5 |
| IGL | immunoglobulin lambda locus |
| JMJD6 | jumonji domain containing 6 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KCTD5 | potassium channel tetramerization domain containing 5 |
| KLF2 | Kruppel-like factor 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK10 | kallikrein-related peptidase 10 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
| MCL1 | myeloid cell leukemia 1 |
| MEIS2 | Meis homeobox 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PEG10 | paternally expressed 10 |
| PER1 | period circadian clock 1 |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PIK3R1 | phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| RGS1 | regulator of G-protein signaling 1 |
| RPL10 | ribosomal protein L10 |
| RSRP1 | arginine/serine-rich protein 1 |
| SIK1 | salt-inducible kinase 1 |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| SYNM | synemin, intermediate filament protein |
| TPBG | trophoblast glycoprotein |
| TSC22D3 | TSC22 domain family, member 3 |
| TSPYL2 | TSPY-like 2 |
| TWIST1 | twist family bHLH transcription factor 1 |
| WARS | tryptophanyl-tRNA synthetase |
| ZFAND5 | zinc finger, AN1-type domain 5 |
| ZFP36 | ZFP36 ring finger protein |
| Symbol | Name |
|---|---|
| ACKR3 | atypical chemokine receptor 3 |
| AGTR1 | angiotensin II receptor, type 1 |
| ALOX5 | arachidonate 5-lipoxygenase |
| ALOX5AP | arachidonate 5-lipoxygenase-activating protein |
| ANXA7 | annexin A7 |
| ARHGAP29 | Rho GTPase activating protein 29 |
| BMP2 | bone morphogenetic protein 2 |
| CA12 | carbonic anhydrase XII |
| CCL20 | chemokine (C-C motif) ligand 20 |
| CD9 | CD9 molecule |
| CHGB | chromogranin B |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| COX7A1 | cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) |
| CRIP1 | cysteine-rich protein 1 (intestinal) |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
| CXCL14 | chemokine (C-X-C motif) ligand 14 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| DCLK1 | doublecortin-like kinase 1 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
| EOGT | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
| EPHA3 | EPH receptor A3 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM134B | family with sequence similarity 134, member B |
| FASTKD5 | FAST kinase domains 5 |
| FERMT1 | fermitin family member 1 |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HPRT1 | hypoxanthine phosphoribosyltransferase 1 |
| ICAM1 | intercellular adhesion molecule 1 |
| IFNGR1 | interferon gamma receptor 1 |
| ITGAM | integrin, alpha M (complement component 3 receptor 3 subunit) |
| ITGAV | integrin, alpha V |
| JAG1 | jagged 1 |
| KRT19 | keratin 19, type I |
| LAMC2 | laminin, gamma 2 |
| LTF | lactotransferrin |
| LXN | latexin |
| MLF1 | myeloid leukemia factor 1 |
| MT1F | metallothionein 1F |
| MTSS1 | metastasis suppressor 1 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NRIP1 | nuclear receptor interacting protein 1 |
| OLFM4 | olfactomedin 4 |
| PDGFA | platelet-derived growth factor alpha polypeptide |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) |
| PLBD1 | phospholipase B domain containing 1 |
| PLIN2 | perilipin 2 |
| PNMA1 | paraneoplastic Ma antigen 1 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PTX3 | pentraxin 3, long |
| QPCT | glutaminyl-peptide cyclotransferase |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B |
| S100A11 | S100 calcium binding protein A11 |
| S100A8 | S100 calcium binding protein A8 |
| S100A9 | S100 calcium binding protein A9 |
| SDC4 | syndecan 4 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SOD2 | superoxide dismutase 2, mitochondrial |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TJP2 | tight junction protein 2 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 |
| VCAM1 | vascular cell adhesion molecule 1 |
