Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
Category | transcriptomics |
Type | small molecule perturbation |
Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
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77 genes differentially expressed following the BRD-K88378636_withaferin-a_HS578T_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
Symbol | Name |
---|---|
1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
ADCK3 | aarF domain containing kinase 3 |
ANKRD10 | ankyrin repeat domain 10 |
AQP1 | aquaporin 1 (Colton blood group) |
ATF3 | activating transcription factor 3 |
BAG3 | BCL2-associated athanogene 3 |
BTG2 | BTG family, member 2 |
C4BPA | complement component 4 binding protein, alpha |
CD69 | CD69 molecule |
CLDN10 | claudin 10 |
DDIT4 | DNA-damage-inducible transcript 4 |
DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
EGR1 | early growth response 1 |
EGR2 | early growth response 2 |
HMOX1 | heme oxygenase 1 |
HSPA1A | heat shock 70kDa protein 1A |
HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
HSPH1 | heat shock 105kDa/110kDa protein 1 |
IDS | iduronate 2-sulfatase |
IER2 | immediate early response 2 |
IER5 | immediate early response 5 |
LYZ | lysozyme |
MUC5B | mucin 5B, oligomeric mucus/gel-forming |
NELL2 | NEL-like 2 (chicken) |
NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 |
PITX1 | paired-like homeodomain 1 |
PLAC8 | placenta-specific 8 |
PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
PROM1 | prominin 1 |
PTPRO | protein tyrosine phosphatase, receptor type, O |
RGS1 | regulator of G-protein signaling 1 |
SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
SFTPB | surfactant protein B |
SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 |
TPPP3 | tubulin polymerization-promoting protein family member 3 |
UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) |
WFS1 | Wolfram syndrome 1 (wolframin) |
ZFP36 | ZFP36 ring finger protein |
ZNF185 | zinc finger protein 185 (LIM domain) |
Symbol | Name |
---|---|
ADORA2B | adenosine A2b receptor |
ARL4C | ADP-ribosylation factor-like 4C |
BASP1 | brain abundant, membrane attached signal protein 1 |
CCDC85B | coiled-coil domain containing 85B |
CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) |
CNN3 | calponin 3, acidic |
CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) |
DACH1 | dachshund family transcription factor 1 |
EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 |
EIF5A | eukaryotic translation initiation factor 5A |
FAM171A1 | family with sequence similarity 171, member A1 |
FXYD3 | FXYD domain containing ion transport regulator 3 |
GJA1 | gap junction protein, alpha 1, 43kDa |
GPRC5B | G protein-coupled receptor, class C, group 5, member B |
GSTM3 | glutathione S-transferase mu 3 (brain) |
H1F0 | H1 histone family, member 0 |
HIST3H2A | histone cluster 3, H2a |
HOXA10 | homeobox A10 |
IGFBP2 | insulin-like growth factor binding protein 2, 36kDa |
LAMA3 | laminin, alpha 3 |
MAP7 | microtubule-associated protein 7 |
MDK | midkine (neurite growth-promoting factor 2) |
MECOM | MDS1 and EVI1 complex locus |
MMP9 | matrix metallopeptidase 9 |
NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
NID2 | nidogen 2 (osteonidogen) |
NTS | neurotensin |
PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
PSD3 | pleckstrin and Sec7 domain containing 3 |
RAB13 | RAB13, member RAS oncogene family |
S100A9 | S100 calcium binding protein A9 |
SPP1 | secreted phosphoprotein 1 |
ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
TIPARP | TCDD-inducible poly(ADP-ribose) polymerase |
TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |