| Dataset | LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [perturbation ID]_[perturbagen]_[cell line]_[time]_[time unit]_[dose]_[dose unit] (LINCS L1000 Connectivity Map) |
| Similar Terms | |
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183 genes differentially expressed following the BRD-K88378636_withaferin-a_MCF7_3_h_3.33_um small molecule perturbation from the LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| 1060P11.3 | killer cell immunoglobulin-like receptor, three domains, pseudogene |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 |
| ADM | adrenomedullin |
| ADRB2 | adrenoceptor beta 2, surface |
| AK4 | adenylate kinase 4 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 |
| ARC | activity-regulated cytoskeleton-associated protein |
| ATF3 | activating transcription factor 3 |
| AUTS2 | autism susceptibility candidate 2 |
| BTG2 | BTG family, member 2 |
| C2 | complement component 2 |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CFD | complement factor D (adipsin) |
| CHEK2 | checkpoint kinase 2 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase |
| CLEC2B | C-type lectin domain family 2, member B |
| COL6A2 | collagen, type VI, alpha 2 |
| COL9A3 | collagen, type IX, alpha 3 |
| CRELD2 | cysteine-rich with EGF-like domains 2 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DACH1 | dachshund family transcription factor 1 |
| DDIT3 | DNA-damage-inducible transcript 3 |
| DDIT4 | DNA-damage-inducible transcript 4 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 |
| DUSP1 | dual specificity phosphatase 1 |
| DUSP2 | dual specificity phosphatase 2 |
| DUSP5 | dual specificity phosphatase 5 |
| EGR1 | early growth response 1 |
| EGR2 | early growth response 2 |
| EGR3 | early growth response 3 |
| ETV1 | ets variant 1 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B |
| FOSL1 | FOS-like antigen 1 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) |
| GPX2 | glutathione peroxidase 2 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 |
| GSDMB | gasdermin B |
| H1FX | H1 histone family, member X |
| HBB | hemoglobin, beta |
| HIST1H2BG | histone cluster 1, H2bg |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMOX1 | heme oxygenase 1 |
| HSPA1A | heat shock 70kDa protein 1A |
| HSPA6 | heat shock 70kDa protein 6 (HSP70B') |
| IER2 | immediate early response 2 |
| IFI27 | interferon, alpha-inducible protein 27 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 |
| JUN | jun proto-oncogene |
| JUNB | jun B proto-oncogene |
| KIAA0355 | KIAA0355 |
| LAMA3 | laminin, alpha 3 |
| LDLR | low density lipoprotein receptor |
| LPL | lipoprotein lipase |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| NEFL | neurofilament, light polypeptide |
| NEFM | neurofilament, medium polypeptide |
| NETO2 | neuropilin (NRP) and tolloid (TLL)-like 2 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 |
| NRN1 | neuritin 1 |
| ORC1 | origin recognition complex, subunit 1 |
| PENK | proenkephalin |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PLBD1 | phospholipase B domain containing 1 |
| PNMA2 | paraneoplastic Ma antigen 2 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 |
| SFN | stratifin |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 |
| SNAP25 | synaptosomal-associated protein, 25kDa |
| SORBS1 | sorbin and SH3 domain containing 1 |
| SOX9 | SRY (sex determining region Y)-box 9 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STMN2 | stathmin 2 |
| TAC1 | tachykinin, precursor 1 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TGFA | transforming growth factor, alpha |
| TMEM176A | transmembrane protein 176A |
| TMEM176B | transmembrane protein 176B |
| TSPAN8 | tetraspanin 8 |
| TYMP | thymidine phosphorylase |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) |
| USP6NL | USP6 N-terminal like |
| WNT5B | wingless-type MMTV integration site family, member 5B |
| ZFP36 | ZFP36 ring finger protein |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
| Symbol | Name |
|---|---|
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase |
| ABLIM1 | actin binding LIM protein 1 |
| ACKR3 | atypical chemokine receptor 3 |
| ALB | albumin |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) |
| BAMBI | BMP and activin membrane-bound inhibitor |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C8ORF4 | chromosome 8 open reading frame 4 |
| CADM1 | cell adhesion molecule 1 |
| CAPN3 | calpain 3, (p94) |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CD24 | CD24 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CES1 | carboxylesterase 1 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene |
| COL4A5 | collagen, type IV, alpha 5 |
| CTBP2 | C-terminal binding protein 2 |
| CTGF | connective tissue growth factor |
| CXCL12 | chemokine (C-X-C motif) ligand 12 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| DSP | desmoplakin |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 |
| F2R | coagulation factor II (thrombin) receptor |
| FAS | Fas cell surface death receptor |
| FCGBP | Fc fragment of IgG binding protein |
| FGFR2 | fibroblast growth factor receptor 2 |
| FHL1 | four and a half LIM domains 1 |
| FNBP1 | formin binding protein 1 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog |
| GATA3 | GATA binding protein 3 |
| GDF15 | growth differentiation factor 15 |
| GRAMD3 | GRAM domain containing 3 |
| HAT1 | histone acetyltransferase 1 |
| IFI44 | interferon-induced protein 44 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 |
| IGF1R | insulin-like growth factor 1 receptor |
| ISG15 | ISG15 ubiquitin-like modifier |
| ITGAV | integrin, alpha V |
| KRT81 | keratin 81, type II |
| LGALS1 | lectin, galactoside-binding, soluble, 1 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LITAF | lipopolysaccharide-induced TNF factor |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LYZ | lysozyme |
| MAP7 | microtubule-associated protein 7 |
| MEF2C | myocyte enhancer factor 2C |
| MPZL2 | myelin protein zero-like 2 |
| MXRA7 | matrix-remodelling associated 7 |
| MYLK | myosin light chain kinase |
| NFIB | nuclear factor I/B |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
| NRIP1 | nuclear receptor interacting protein 1 |
| OPN3 | opsin 3 |
| OXA1L | oxidase (cytochrome c) assembly 1-like |
| PCP4 | Purkinje cell protein 4 |
| PLCB4 | phospholipase C, beta 4 |
| PPAP2C | phosphatidic acid phosphatase type 2C |
| PRKD3 | protein kinase D3 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) |
| RBP4 | retinol binding protein 4, plasma |
| RPL31 | ribosomal protein L31 |
| S100A7 | S100 calcium binding protein A7 |
| S100A9 | S100 calcium binding protein A9 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SFRP1 | secreted frizzled-related protein 1 |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC38A1 | solute carrier family 38, member 1 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing |
| SOX4 | SRY (sex determining region Y)-box 4 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SYNJ2 | synaptojanin 2 |
| TACSTD2 | tumor-associated calcium signal transducer 2 |
| TFRC | transferrin receptor |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) |
| TGFBR3 | transforming growth factor, beta receptor III |
| THBS1 | thrombospondin 1 |
| TRD | T cell receptor delta locus |
| TRPS1 | trichorhinophalangeal syndrome I |
| VIM | vimentin |
| VLDLR | very low density lipoprotein receptor |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 |
| WFDC1 | WAP four-disulfide core domain 1 |
| XIST | X inactive specific transcript (non-protein coding) |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
